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항암화학요법 후 난소의 광학현미경적 변화

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Author(s)
최은주차순도박윤정남동호이은우이태성이탁박관규
Keimyung Author(s)
Cha, Soon DoLee, Tae SungLee, TakPark, Kwan Kyu
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Dept. of Pathology (병리학)
Journal Title
대한부인종양콜포스코피학회지
Issued Date
1993
Volume
4
Issue
4
Abstract
To examine the cytotoxic effect of chemotherapy on the ovary, 23 cases undergoing oophorectomy with radical hysterect,orny in premenopausal wemen receiving induction chemotherapy with cisplatin and 5- fluomouracil for carcinoma of the cervix between March, 1989 and December, 1992 were studied by light microscopy. Out of 23 cases, 19 (82.6%) showed vascular congestion and 12(52.1%) revealed hemorrhage around folliele and within corpus luteum. The follicular structure was desLroyed in 16 cnses (69.5% ) and oocytes of ovums were lost in 17 cases.'I'he mechanism of injury of the ovarian structures after combination chemotherapy with cisplatin and 5-fluorouracil is considered to be caused by secondary cell damage following circulatory disturbance of direct toxicity on fallicular cells of oocytes.
Alternative Title
Light Microscopic Study of the Ovary in Patients Receiving Chemotherapy
Keimyung Author(s)(Kor)
차순도
이태성
이탁
박관규
Publisher
School of Medicine
Citation
최은주 et al. (1993). 항암화학요법 후 난소의 광학현미경적 변화. 대한부인종양콜포스코피학회지, 4(4), 81–89.
Type
Article
ISSN
1226-1742
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38675
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
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