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상부요로 이행상피 세포암에서 방광에 속발되는 위험인자 및 생존율

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Author(s)
최호철박철희김천일이성준Ho Cheol ChoiChoal Hee ParkChun Il KimSung Choon Lee
Keimyung Author(s)
Park, Choal HeeKim, Chun IlLee, Sung Joon
Department
Dept. of Urology (비뇨의학)
Journal Title
대한비뇨기과학회지
Issued Date
1993
Volume
34
Issue
4
Abstract
Transitional cell carcinoma (TCC) of the upper urinary tract is a relatively rare malignancy that accounts for only 5 to 10% of all urothelial tumors. A patients with an upper tract TCC has a 25.8 % to 35.8 % probability of developing a subsequent TCC of the bladder. usually on the source of the upper tract TCC lesion. A retrospective analysis of 46 patients with an upper urinary tract (UUT) TCC which was treated surgically. was performed in relation to the development of a subsequent bladder tumor. In this study, we tried to clarify the risk factors of bladder tumor recurrence following surgery for UUT tumor and the survival rates of UUT tumor with and without a subsequent bladder tumor. Treatment for UUT tumor was total nephroureterectomy with bladder cuff excision in all 46 patients. In 25 of the 46 patients (54.3%), bladder tumors developed following surgery of a UUT tumor. Transurethral resection of bladder tumor and intravesical chemo- or immunotherapy were performed in all patients with subsequent bladder tumor. Patients with a subsequent bladder tumor consisted of multiple UUT tumor (12 patients), lower ureteral tumor ( 7 patients) and renal pelvis tumor (6 patients). The follow-up period varied from 24 months to 118 rnonths, with a mean of 64 months. Mean number of bladder recurrence was 2.5. The interval from surgery for UUT tumor to diagnosis of the initial bladder recurrence ranged from 8 months to 28 months, with a mean of 18 months. High stage and grade ( >p T2, >G II ), more than two tumors in the UUT and vascular or lymphatic invasion had a significant influence on the rate or bladder tumor recurrence (p<0.05). Difference of 5-rear survival rate of UUT tumor was insignificant in patient with (58% ) and without (62% ) subsequent bladder tumor (p<0.05).
Key word : Upper tract transitional cell carcinoma, Subsequent bladder tumor, Risk factors
Alternative Title
Risk Factors and Survival in Patients with Recurrence of Bladder Tumors following Surgery for Transitional Cell Carcinoma of the Upper Urinary Tract
Keimyung Author(s)(Kor)
박철희
김천일
이성준
Publisher
School of Medicine
Citation
최호철 et al. (1993). 상부요로 이행상피 세포암에서 방광에 속발되는 위험인자 및 생존율. 대한비뇨기과학회지, 34(4), 613–618.
Type
Article
ISSN
2005-6737
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38741
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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