요분리 그람음성균의 병원성과 항균제내성

Abstract

This study was performed for the assessing the distribution, drug resistance and its transferability, and cell agglutinating ability of Enterobacteriaceae isolated from urine of patients with urinary tract infection. Total 164 strains of Strains of Enterobacteriaceae including, 91 strains of E. coli, 35 strains of klebsiella, 23 strains of Proteus, 6 strains of Serratia, 6 strains of Citrobacter, 3 strains of Enterobacteriaceae were isolated from urine. In the cell agglutinating test, most organisms, except Proteus, showed mannose resistant agglutination. Among organisms tested more than 20 strains, E. coli showed highest frequency of cell agglutination. In the comparison of cell agglutinating characteristics of E. coli and Klebsiella isolated from urine and other sources urinary isolates of E. coli showed higher frequency of agglutination and greater agglutinating potency than isolates from other sources, but Klebsiella showed little difference between isolates of urine and other sources. Urinary isolates usually showed high frequency of resistance to penicillin(90% ), ampicillin(89%). sulfamethoxazole(69%), tetracycline(66%), chloramphenicol(53% ), but showed low frequency of resistance to moxalactam( 1% ), amikacin(2%), and nalidixic acid ( 9% ), and these resistance were highly transferable resistance mediated by R plasmid. Key word : Mannose-resistant agglutination, R-plasmid.