계명대학교 의학도서관 Repository

진행된 상부요로 이행상피세포암에 대한 술후 보조적 M-VAC(Methotrexate, Vinbastine, doxorubicin and Cisplatin)병용 화학요법의 효과

Metadata Downloads
Author(s)
서병욱하달봉박철희이성준Byung Wook SeoDal Bong HaChoal Hee ParkSung Choon Lee
Keimyung Author(s)
Park, Choal HeeLee, Sung Joon
Department
Dept. of Urology (비뇨의학)
Journal Title
대한비뇨기과학회지
Issued Date
1992
Volume
33
Issue
4
Abstract
We treated 11 patients with advanced transitional cell carcinoma of upper urinary tract with adjuvant M-VAC chemotherapy and their median survival time was compared with 9 patients without M-VAC chemotherapy as e historical group. The total number of cycles per each patient ranged from 1 to 5 with a mean of 3.4. Of these patients, 8 patients could be evaluated for response and 4 patients were responded (2 complete and 2 incomplete. response rate 50%). The median duration of response was 26 months for complete responders and 4.5 months for incomplete responders. The median duration of survival for all chemotherapy group, complete responders, progression and historical control group were 22, 23+. 14 and 21 months. respectively. Median survival was 22 months in all 11 patients. 23+ months in clinical responders, 14 months in progression and 21 months in historical control group. Although overall survival was not prolonged significantly in chemotherapy than the historical control group, M-VAC was effective in small proportion of patients (CR: 2/8). The duration of survival of the patients with complete remission was prolonged significantly.
Key word : advanced TCC, M-VAC chemotherapy.
Alternative Title
The Effect of Adjuvant M-VAC (Methotrexate, Vinblastine, Doxorubicin and Cisplatin) Chemotherapy on Advanced Transitional Cell Carcinoma of the Upper Urinary Tract
Keimyung Author(s)(Kor)
박철희
이성준
Publisher
School of Medicine
Citation
서병욱 et al. (1992). 진행된 상부요로 이행상피세포암에 대한 술후 보조적 M-VAC(Methotrexate, Vinbastine, doxorubicin and Cisplatin)병용 화학요법의 효과. 대한비뇨기과학회지, 33(4), 632–636.
Type
Article
ISSN
2005-6737
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38799
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.