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표재성 방광암의 BCG방광내 주입요법

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Author(s)
박철희이성준Choal Hee ParkSung Choon Lee
Keimyung Author(s)
Park, Choal HeeLee, Sung Joon
Department
Dept. of Urology (비뇨의학)
Journal Title
대한비뇨기과학회지
Issued Date
1988
Volume
29
Issue
3
Abstract
Intravesical Bacillus Calmette-Guerin(BCG) Has been shown to be effective therapy and prophylaxis against recurrent tumor in patients with superficial bladder cancer(stages O and A), including carcinoma in situ. Tice-Chicago strain bacillus Calmette-Guerin was used to treat superficial transitional cell carcinoma of the bladder in 26 patients between July, 1985 and March, 1988. A variety of different BCG treatment regimens have been used that vary in intensity. In general, treatment results have been more favorable with intensive regimens. However, the toxicity also has been substantially greater with intensive regimens. The optimal regimen has yet to be determined. Our treatment regimen of 120mg. Tice-Chicago strain BCG weekly for 6 weeks and then monthly for 3 months was well tolerated. 20 patients had a complete response and 6 patients had a tumor recurrence at 21 months mean follow-up, resulting in 77% of response rate. Side effects during or shortly after treatment were minor and self- limiting in the majority of patients(fever, bladder irritability and hematuria). This experience supports the efficacy of bacillus Calmette-Guerin as a cost-effective, well- tolerated treatment modality for patients with superficial transitional cell carcinoma of the bladder.
Alternative Title
BCG(Bacillus Calmette-Guerin) for Superficial Transitional Cell Carcinoma of the Bladder
Keimyung Author(s)(Kor)
박철희
이성준
Publisher
School of Medicine
Citation
박철희 et al. (1988). 표재성 방광암의 BCG방광내 주입요법. 대한비뇨기과학회지, 29(3), 387–393.
Type
Article
ISSN
2005-6737
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38806
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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