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한국인에서 혈중 전립선특이항원의 연령별 정상치

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Author(s)
전형진김영식강대룡남정모김천일성도환김세중전상현조인래조진선홍성준최영득Hyung Jin JeonYoung Sik KimDae Ryeong KangChung Mo NamChun Il KimDo Hwan SeongSe Joong KimSang Hyeon CheonIn Rae ChoJin Seon ChoSung Joon HongYoung Deuk Choi
Keimyung Author(s)
Kim, Chun Il
Department
Dept. of Urology (비뇨의학)
Journal Title
대한비뇨기과학회지
Issued Date
2006
Volume
47
Issue
6
Abstract
Purpose: The level of serum prostate-specific antigen (PSA) varies according to both age and race. It is known that the level of PSA increases with age, and that Asians have a lower incidence of prostate cancer and levels of PSA than Caucasians. In this study, the variation in the serum PSA level in samples collected from general populations were used to find an actual standard age-specific PSA reference range for Koreans.
Materials and Methods: Patients who received serum PSA level checkups, between November 1998 and July 2005, at 8 domestic hospitals, were selected for the investigation. The PSA levels of 120,439 adult males, aged between 30 and 80 years, were measured, and those lower than 10ng/ml were analyzed. To estimate the increase in the level of serum PSA according to age, a simple linear regression analysis was carried out.
Results: The mean PSA level reference ranges according to age were 1.88, 1.92, 2.37, 3.56 and 5.19ng/ml for those in their thirties, forties, fifties, sixties and seventies, respectively. The rates of PSA change were 0.0023, 0.0175 and 0.0499 for those in their forties, fifties and sixties, respectively, indicating the rates of PSA level change increase steady with age, but these increases are greater for those in their fifties and most severe after their sixties. The level of age-specific PSA reference in Korean men was lower than that of men from Western countries.
Conclusions: The age-specific PSA reference levels, as found in pre-existing literature, showed differences between races, with the overall reference levels being low for domestic data. The standard reference level of agespecific PSA for the screening of prostate cancer may be lower in Korean men than those from Western countries. (Korean J Urol 2006;47:586-590)
Alternative Title
Age-Specific Reference Ranges for Serum Prostate-Specific Antigen in Korean Men
Keimyung Author(s)(Kor)
김천일
Publisher
School of Medicine
Citation
전형진 et al. (2006). 한국인에서 혈중 전립선특이항원의 연령별 정상치. 대한비뇨기과학회지, 47(6), 586–590. doi: 10.4111/kju.2006.47.6.586
Type
Article
ISSN
2005-6737
DOI
10.4111/kju.2006.47.6.586
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38813
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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