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자궁경부암에서 종양의 맥관 형성이 암전이에 미치는 영향

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Author(s)
신해영차순도이태성Hae Young ShinSoon Do ChaTae Sung Lee
Keimyung Author(s)
Cha, Soon DoLee, Tae Sung
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
대한산부인과학회잡지
Issued Date
1998
Volume
41
Issue
5
Abstract
To investigate the correlation between tumor angiogenetic activity and lymph node metastasis in cervical carcinoma, immunohistochemical staining with antifactor Ⅷ related antigen (F-Ⅷ RAg) antibody was used. Seventy-one specimens resected from the patients with squamous cell carcinoma of the uterine cervix were analyzed by staining with a monoclonal antibody against Factor Ⅷ-related antigen. Correlations among the microvessel count(the mean number of microvessels in three areas of highest vascular density at 200 times magnification), various clinicopathologic factors, and disease free survivial rates were studied. The microvessel count (MVC) (range 6.3∼29.7, mean=14.6±4.8) were higher in the advanced stages. MVC had no correlation with the other clinicopathologic factors, i.e. lymph node status, invasion depth, lymphovascular space invasion, cell type, and histologic grade. There was statistically significant correlations between the disease free survival rates and lymph node status. However, there was no significant correlations in disease free survival rates with microvessel count. These results showed that microvessel count, may not be related to lymph node status and prognosis of the disease.
Key word : Microvessel cunt; Lymph node status; Cervical cancer
Alternative Title
The Impact of Tumor Angiogenesis on Pelvic Node Metastasis in Cervical Cancer
Keimyung Author(s)(Kor)
차순도
이태성
Publisher
School of Medicine
Citation
신해영 et al. (1998). 자궁경부암에서 종양의 맥관 형성이 암전이에 미치는 영향. 대한산부인과학회잡지, 41(5), 1479–1484.
Type
Article
ISSN
0494-4755
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38845
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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