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자간전증에서 혈액응고 및 섬유소용해작용의 변동

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Author(s)
이재호김택훈서영욱전동석J.H. LeeT.H. KimY.U. SuhD.S. Jeon
Keimyung Author(s)
Kim, Taek HoonSuh, Young WookJeon, Dong Seok
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Dept. of Laboratory Medicine (진단검사의학)
Journal Title
대한산부인과학회잡지
Issued Date
1994
Volume
37
Issue
1
Abstract
To investigate the alterations of clotting and fibrinolytic activities in preeclampsia, the platelet, fibrinogen, D-dimer, plasminogen, antithrombin III activity, α2-plasmin inhibitor and protein C were assayed. The peripheral venous blood was sampled from 20 normal pregnant women as control group and 35 preeclamptic pregnant women as study group in the third trimester.
The age and maternal body weight revealed no statistical difference between control and study group. The gestational age was statistically different (p<0.001) between control (40.5±0.6 weeks) and study group (35.8±0.8 weeks), but all in the third trimester. The neonatal body weight was also statistically different (p<0.005) between control (3552.5±176.4g) and study group (2472.9±357.9g).
There was no statistical difference between normal pregnancy and preeclampsia in D-dimer, plasminogen and protein C. The platelet count was decreased in preeclampsia compared with normal pregnancy, but statistically not significant. There was a decreasing tendnecy (p<0.1, p>0.05) of α2-plasmin inhibitor in preeclampsia (82.0±9.8%, n=25) compared with normal pregnancy (96.0 ±7.2 %).
The fibrinogen showed statistically significant decrease (p<0.001) in preeclampsia.
Alternative Title
Clotting and Fibrinolytic Activities in Preeclampsia
Keimyung Author(s)(Kor)
김택훈
서영욱
전동석
Publisher
School of Medicine
Citation
이재호 et al. (1994). 자간전증에서 혈액응고 및 섬유소용해작용의 변동. 대한산부인과학회잡지, 37(1), 3~14-3~14.
Type
Article
ISSN
0494-4755
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38874
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학)
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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