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임신 중 말초 혈액 내 B임파구, T임파구 및 그 아형의 변화

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Author(s)
김택훈조치흠윤성도서영욱전동석김재룡T.H. KimC.H. ChoS.D. YoonY.W. SuhD.S. JeonJ.R. Kim
Keimyung Author(s)
Kim, Taek HoonCho, Chi HeumYoon, Sung DoSuh, Young WookJeon, Dong SeokKim, Jae Ryong
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Dept. of Laboratory Medicine (진단검사의학)
Journal Title
대한산부인과학회잡지
Issued Date
1990
Volume
33
Issue
5
Abstract
Many studies have been performed to evaluate of lymphocyte subsets in pregnancy as well as functional aspects of cell mediated immunity during pregnancy. However, studies of circulating B lymphocyte, T lymphocyte and subsets during pregnancy have yield conflicting results. The aubhors evaluated the B lymphocyte, T lymphocyte and subsets at various stage of pregnancy and nonpregnant controls. As a group, pregnant women had significantly (p < 0.05) lower total lymphocyte component ratio in second trimester (20.8 ± 4.4 %) and third trimester (20.4 ± 5.5 %) than did controls (32.6 ± 8.2 %) and first trimester pregnant women. The mean absolute number of lymphocyte in pregnancy is 190.4 ± 540.9/mm3. Component ratio of B lymphocyte in pregnant women is 9.7 ± 2.6 % and mean absolute number is 188.8 ± 66.6/mm3, which are not significantly different compared with control group. Component ratio of T lymphocyte is significantly (p < 0.05) higher in second trimester pregnant women (86.2 ± 1.6 %) and third trimester pregnant women (86.0 ± 2.8 %) than first trimester pregnant women (79.2 ± 5.6 %) and nonpregnant control group (79.7 ± 3.1 %). Component ratio of T4 cells is significantly (p < 0.05) higher is second trimester pregnant women (47.8 ± 5.4 %) and third trimester pregnant women (47.0 ± 6.1 %) than control group (41.7 + 3.6 %) and first trimester pregnant women (40.7 ± 8.3 %). Absolute number of T4 cells is significantly (p , 0.05) higher in pregnant women (768.8 ± 261.2/mm) than control group (587.2 ± 149.9/mm). Component ratio of T8 cells is lower in first trimester pregnant women (36.9 ± 5.7 %) than control group (38.4 ± 3.2 %), but which is not significantly different. Absolute number of T8 cells is significantly (p < 0.05) higher in first trimester pregnant women(736.5 + 212.8/mm) than control group (539.4 ± 133.9/mm). T4/T8 ratio in pregnant women (1.21 ± 0.34) is not statistically different compared with control with control group (1.09 ± 0.14). T/B lymphocyte component ratio is significantly (p < 0
Alternative Title
Circulating B Lymphocyte, T Lymphocyte and Its Subsets in Pregnancy
Keimyung Author(s)(Kor)
김택훈
조치흠
윤성도
서영욱
전동석
김재룡
Publisher
School of Medicine
Citation
김택훈 et al. (1990). 임신 중 말초 혈액 내 B임파구, T임파구 및 그 아형의 변화. 대한산부인과학회잡지, 33(5), 569–575.
Type
Article
ISSN
0494-4755
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38925
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학)
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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