연탄가스중독의 후유증으로 발병한 무도성발리즘에 동반된 신경이완제 악성증후군 1례

Abstract

Neurologic complications such as mental status changes, incontinence, gait disturbances, extrapyramidal symptoms may be delayed days or weeks after exposure to carbon monoxide but hyperkinesia such as choreoballism and athetosis rarely occurs as symptoms of delayed neurologic complication of carbon monoxide intoxication. Neuroleptic malignant syandrome (NMS) is a rare, potentially fatal drug-induced disorder associated with hyperthermia, muscle rigidity, autonomic instability, mental dysfunction and various dyskinesia. Various major neuroleptic drugs seem to be its culprits. We describe a 24-year-old female patient who presented with NMS following administration of haloperidol for choreoballism, a symptom of delayed neurologic sequelas after carbon monoxide intoxication, with a review of the literature.

저자들은 연탄가스중독으로 회복된 뒤 24일 후에 지연성 합병증으로 발병한 무도성 발리즘을 주소로 입원하여 haloperidol을 투여 받던 중 신경이완제 악성증후군이 발병한 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.