두개강내 상의세포종의 임상적 병리적 관계

Abstract

The clinical and pathological features were analyzed for 11 cases with intracranial ependymona treated surgically at the Keimyung University. Dongsan Medical Center during the years 1987 to 1992. Tumor histology was reviewed individually and grouped into the three categories(Categories Ⅰ to Ⅲ) according to the pathologic grade used by Nazar, et al. The correlation between the pathologic grade and prognosis after surgery was investigated. There were 2 cased(18%) with category Ⅰ histology, 5(45%) with category Ⅱ histology, and 4(36%) with category Ⅲ category. The high recurrent rate, short recurrent interval, high rate of cerebrospinal fluid seeding and poor outcome were noted in with category Ⅲ histology. The authors also investigated the recurrent interval according to the degree of tumor resection. The mean recurrent interval after surgery was 12 months in cased of subtotal resection and 33 months in a case of total resection. Tumors resected subtotally showed response to radiation and chemotherapy. In conclusion, the pathologic grade and the degree of tumor resection were regarded as important prognostic factors after surgery. Aggressive surgery with chemotherapy or radiotherapy were required in the management of intracranial ependymoma.