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가토 태자의 하악골골절 치유에 관한 조직학적 연구

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Author(s)
홍성주한기환강진성Sung Joo HongKih Wan HanJin Sung KangSangpyo Kim
Keimyung Author(s)
Han, Ki HwanKang, Jin Sung
Department
Dept. of Plastic Surgery (성형외과학)
Journal Title
대한성형외과학회지
Issued Date
1995
Volume
22
Issue
5
Abstract
Although clinical and experimental findings have demonstrated that fetal soft-tissue wounds heal without scarring, very little is known about the process of fetal bone healing. This study examined fetal membranous bone healing in utero, histologically, without fracture fixation in a fetal rabbit model. Our study group consisted of 50 live fetuses (from 30 New Zealand White rabbit). An incisional fracture of the fetal mandibular body was performed on fetal rabbit at 24 days' gestation (term=31days) In utero. The other side mandibular body (not operated on) was used as a control. The specimens havested 1, 3, 5, 7 and 10 days after fracture. Twenty-five fetuses survived the Procedure and were alive at the time of harvest. Histologically, the incisional fracture sites demonstrated fibrin with little hemorrhage at 1 day. There was no evidence of hematoma formation or inflammatory reaction. At 3 days, there was no fibrin or inflammatory cells with more infiltration of mesenchymal cells in fracture sites. The fracture site demonstrated new bone formation at 5 days. At 7 days, the fracture sites healed woven bone completely filling the fracture gap. The fracture sites demonstrated more mature bone at 10 days. The results of this study demonstrated that the fetal membranous bone healing was rapid and no evidence of hematoma formation or inflammatory reaction. Key words: Mandibular fracture healing ,Fetal surgery
Alternative Title
A HISTOLOGICAL STUDY OF MANDIBULAR FRACTURE HEALING IN THE FETAL RABBIT
Keimyung Author(s)(Kor)
한기환
강진성
Publisher
School of Medicine
Citation
홍성주 et al. (1995). 가토 태자의 하악골골절 치유에 관한 조직학적 연구. 대한성형외과학회지, 22(5), 945-953.
Type
Article
ISSN
1015-6402
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38982
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Plastic Surgery (성형외과학)
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