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중증근무력증에서 혈청 항아세틸콜린 수용체 항체, Interleukin-2 및 가용성 Interleukin-2 수용체 농도의 변동

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Author(s)
임정근박준형유영수이상도박영춘Jeong-Geun LimJun-Hyung ParkYoung-Soo YouSang-Do YiYoung-Choon Park
Keimyung Author(s)
Lim, Jeong GeunYi, Sang DoPark, Young Chun
Department
Dept. of Neurology (신경과학)
Journal Title
대한신경과학회지
Issued Date
1996
Volume
14
Issue
3
Abstract
Objective/Background : Serum levels of anti-acetylcholine receptor antibody (AChR-Ab), interleukin-2 (IL-2) and soluble interleukin-2 receptor (sIL-2R) may represent markers of disease severity in myasthenia gravis (MG). This study was performed to evaluate the correlations between disease severity and immunological parameters such as serum AChR-Ab, IL-2 and sIL-2R level and between each immunological parameters.
Methods : Serum levels of AChR-Ab, IL-2 and sIL-2R were measured in 30 MG patients and in 22 healthy controls.
Results : Serum levels of AChR-Ab and sIL-2R were higher in MG than in healthy controls (p< 0,01) . The occurrence of IL-2 positive serum samples was 46.7% in MG but none in controls. There were no significant correlations between disease severity and immunological parameters and between each immunological parameters.
Conclusions : Serum IL-2 and sIL-2R levels may not represent markers of disease severity in MG, In order to further document the correlation between each parameters, follow-up of individual patients with serial serum samplings may be necessary.
Alternative Title
Serum Anti-Acetylcholine Receptor Antibody, Interleukin-2 and Soluble Interleukin-2 Receptor Levels in Myasthenia Gvavis
Keimyung Author(s)(Kor)
임정근
이상도
박영춘
Publisher
School of Medicine
Citation
임정근 et al. (1996). 중증근무력증에서 혈청 항아세틸콜린 수용체 항체, Interleukin-2 및 가용성 Interleukin-2 수용체 농도의 변동. 대한신경과학회지, 14(3), 773–780.
Type
Article
ISSN
1225-7044
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39023
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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