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백서의 좌골신경 절단 후 비복근의 자기공명영상 신호강도 변화와 근전도 소견의 관계

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Author(s)
이주환이장철김동원박기영이성문Joo Hwan LeeJang Chul LeeDong Won KimKi Young ParkSung Moon Lee
Keimyung Author(s)
Lee, Jang ChullKim, Dong WonPark, Gi YoungLee, Sung Mun
Department
Dept. of Neurosurgery (신경외과학)
Dept. of Rehabilitation Medicine (재활의학)
Dept. of Radiology (영상의학)
Journal Title
대한신경외과학회지
Issued Date
2000
Volume
29
Issue
1
Abstract
Objectives:The evaluation of peripheral nerve injuries has traditionally relied on a clinical history, physical examination, and electrodiagnostic studies. The purpose of the present study was to examine serial magnetic resonance image(MRI) changes following acute muscle denervation under experimental conditions and to identify potential advantages and disadvantages of this use of MRI.
Methods:An experimental transection of right sciatic nerve on Spargue-Dawley rats was performed. MRI was performed with T1-weighted spin-echo and STIR sequences. The imaging findings were compared with EMG in order to determine its sensitivity relative to this standard procedure. A simultaneous histopathological study provided information about the morphological basis of the imaging findings. Signal intensities were expressed as a ratio of abnormal to normal.
Results:The signal intensity ratio of muscles with the STIR sequence was increased significantly at 2 weeks after sciatic nerve transection(p<0.05), although definite signal change was seen as early as 4 days postdenervation in one. EMG revealed significant denervation potential from 3 days after nerve transection. Diffuse cell atrophy was revealed hostologically at 2 weeks after transection, which was at the same time of significant signal change in MRI.
Conclusion:MRI signal changes in denervated muscles secondary to nerve injury correlate with the degree of muscle atrophy on histologic examination. In addition to EMG, MRI can document the course of muscle atrophy and mesenchymal abnormalities in denervation. These results indicate that MRI can play a complementary role in the evaluation of patients with denervation.
Alternative Title
Correlation between Magnetic Resonance Image Signal Changes and Electromyographic Findings after Sciatic Nerve Transection in the Rat
Keimyung Author(s)(Kor)
이장철
김동원
박기영
이성문
Publisher
School of Medicine
Citation
이주환 et al. (2000). 백서의 좌골신경 절단 후 비복근의 자기공명영상 신호강도 변화와 근전도 소견의 관계. 대한신경외과학회지, 29(1), 101–107.
Type
Article
ISSN
1225-8245
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39146
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
1. School of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학)
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