계명대학교 의학도서관 Repository

소아 시교차-시상하부 신경교종의 치료

Metadata Downloads
Author(s)
도홍직김일만이창영손은익김동원임만빈김상표Hong-Jik DohIl-Man KimChang Young LeeEun Ik SonDong Won KimMan Bin YimSang Pyo Kim
Keimyung Author(s)
Kim, ElLee, Chang YoungSon, Eun IkKim, Dong WonYim, Man BinKim, Sang Pyo
Department
Dept. of Neurosurgery (신경외과학)
Dept. of Pathology (병리학)
Journal Title
대한신경외과학회지
Issued Date
2001
Volume
30
Issue
9
Abstract
Objective:Management strategies for pediatric chiasmatic-hypothalamic gliomas(CHG) include surgery, irradiation, chemotherapy and a combination of these modalities. This study was performed in order to compare the efficacy of various methods of treatment and to describe its optimal management.
Material and Method:We have reviewed the results of management of 6 children with a diagnosis of CHG, who were observed closely during the last 8 years. The patients were aged 7 months to 15 years. Our patients presented with diencephalic syndrome, endocrine dysfunction, and progressive visual loss. None of these had evidence of neurofibromatosis-1. Treatment consisted of surgery alone(2), surgry and irradiation(2), surgery, irradiation and chemotherapy(1), and surgery and chemotherapy(1).
Results:Four children had large exophytic suprasellar tumors and two showed diffuse midline lesions. Obstructive hydrocephalus was present in all patients. Pathologic examination revealed anaplastic astrocytoma in 1 and lowgrade astrocytoma in 5. Two patients, recently treated with radiation therapy following radical subtotal resection, showed significant tumor reductions and good clinical status. Four patients had partial tumor resection. Of these patients, two developed disease stabilization during follow-up period of 7 and 8 years, respectively. Life-threatening complications were noted in remaining two patients.
Conclusion:CHG may follow an unpredicatable course and show a various reponse to each treatment modality. Further studies are indicated to define the optimal method of treatment of CHG in childhood.
Alternative Title
Management of Chiasmatic-Hypothalamic Gliomas in Children
Keimyung Author(s)(Kor)
김엘
이창영
손은익
김동원
임만빈
김상표
Publisher
School of Medicine
Citation
도홍직 et al. (2001). 소아 시교차-시상하부 신경교종의 치료. 대한신경외과학회지, 30(9), 1115–1119.
Type
Article
ISSN
1225-8245
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39173
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.