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창상 환경에 따른 돼지 복합피부조직이식의 생착에 관한 연구

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Author(s)
원동철손대구한기환박관규Dongchul WonDaegu SonKihwan HanKwankyu Park
Keimyung Author(s)
Son, Dae GuHan, Ki HwanPark, Kwan Kyu
Department
Dept. of Plastic Surgery (성형외과학)
Dept. of Pathology (병리학)
Journal Title
대한성형외과학회지
Issued Date
2003
Volume
30
Issue
6
Abstract
Composite grafts have served as a versatile tool in plastic surgery, but their usefulness has been limited by unpredictable survival in the case of larger defects. We compared composite grafts take rates in a wet environment, known to be ideal for wound healing, a moist environment with mild compression, and a dry environment in an established porcine model. The subjects of this study were 7 female Yorkshire pigs with 54 composite grafts. These 3x3cm sized composite grafts, composed of skin and subcutaneous fat, were harvested as samples on the back of the subjects to be reimplanted based on random patterns. Group I was introduced to a wet environment with sufficient antibiotic ointment and semi-occlusive polyurethane film(Opsite(R)) coverage, while group II was introduced to a moist environment and mild compression with hydrocellular foam dressing(Allevyn(R) and Opsite(R)coverage. Meanwhile, group III was applied simply with dry. Two weeks after the grafting, the survival rates of groups I(89%) and II(83%) were significantly higher than those of group III(31%)(p<0.05). The degrees of inflammation and fibrosis in groups I and II were less than in group III. Epithelial connections between the grafts and the recipients were the fastest in group II. According to the results of this study, maintaining a wet environment and mild compression may not only increase the composite graft take rate but also increase the size of grafts that could be transferred successfully.
Alternative Title
Accelerated Healing of Composite Graft in a Wet Environment: a Pig Model
Keimyung Author(s)(Kor)
손대구
한기환
박관규
Publisher
School of Medicine
Citation
원동철 et al. (2003). 창상 환경에 따른 돼지 복합피부조직이식의 생착에 관한 연구. 대한성형외과학회지, 30(6), 801–808.
Type
Article
ISSN
1015-6402
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39204
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Plastic Surgery (성형외과학)
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