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내측두엽간질 환자에서 전측두엽절제술이 지능과 기억기능에 미치는 효과: 1년 추적

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Author(s)
김홍근이상도손은익김지언Hongkeun KimSangdoe YiEun Ik SonJieun Kim
Keimyung Author(s)
Yi, Sang DoSon, Eun Ik
Department
Dept. of Neurology (신경과학)
Dept. of Neurosurgery (신경외과학)
Journal Title
대한신경과학회지
Issued Date
2006
Volume
24
Issue
4
Abstract
Background: The aim of this study was to identify factors predicting intellectual and memory changes following anterior temporal lobectomy (ATL) for mesial temporal lobe epilepsy (TLE). Methods: The sample consisted of 31 patients who underwent ATL for treatment of medically intractable TLE. All patients were administered intellectual and memory tests preoperatively and postoperatively. Results: All statistically significant intellectual and memory changes at 1-year follow-up were in the direction of improvement. Left vs. right ATL had significantly differential effects on verbal intelligence and verbal memory, reflecting greater decline (or less improvement) following a left ATL. A later onset age of seizures, an older age at surgery, and a higher presurgical cognitive performance predicted a greater cognitive decline following an ATL. Conclusions: At 1-year after ATL, most cognitive functions showed either no significant changes or significant changes in a favorable direction. Decreased verbal functions following a left ATL was the area of greatest potential neuropsychological morbidity associated with ATL. Greater cognitive decline following ATL was predicted by later onset age of recurrent seizures, older age at time of surgery, and higher presurgical cognitive performance.
Alternative Title
Effects of Anterior Temporal Lobectomy for Mesial Temporal Lobe Epilepsy on Intellectual and Memory Functions: 1-Year Follow-up
Keimyung Author(s)(Kor)
이상도
손은익
Publisher
School of Medicine
Citation
김홍근 et al. (2006). 내측두엽간질 환자에서 전측두엽절제술이 지능과 기억기능에 미치는 효과: 1년 추적. 대한신경과학회지, 24(4), 347–355.
Type
Article
ISSN
1225-7044
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39281
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
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