계명대학교 의학도서관 Repository

정형외과 수술에 따른 C-reactive protein의 변화

Metadata Downloads
Author(s)
송광순강철형민병우조영래
Keimyung Author(s)
Song, Kwang SoonKang, Chul HyungMin, Byung Woo
Department
Dept. of Orthopedic Surgery (정형외과학)
Journal Title
대한정형외과학회지
Issued Date
1997
Volume
32
Issue
3
Keyword
C-reactive protein (CRP)Normal changesOrthopaedic surgeries
Abstract
To define the effectiveness of C-reactive protein(CRP) as indicator for early detection of the post- operative infection, it is essential to exclude possible normal changes of CRP influenced by surgery itself. We analyzed 44 patients who had done orthopaedic surgeries without any evidence of infection preoperative and postoperatively from May to Aug. 1995 at Dongsan medical center, Keimyung University. We checked the levels of Erythrocyte sedimentation rate(ESR) and CRP levels at preop- erative and postoperative 1, 3, 5, 7, 9, 11, 13, 15, 17, 19 and 21st day in all cases. In all cases, ESR increased up to 60mm/hr maximally and CRP increased to more than 10mg/dl at least one occasion within the first 3 weeks postoperatively. However CRP showed more rapid changes than ESR. The mean value of the CRP was increased maximally(7.2mg/dl) at 3 day after operation and then decreased rapid until 11 day. ESR was also increased at 3 day after operation, but it sustained high level until 21 day after operation. CRP appears to be more sensitive and rapid indicator as an acute phase reactant for the operation itself because CRP revealed more earlier and accentuated change after the operation. The changes of CRP showed same pattern regardless of operation time, use of tourniquet, use of transfusion and gender. In conclusion, within 3 day after operation, the high titer of CRP can not to be an indicator for early detection of the infection, because normal high titer can be developed by surgery itself. If there notes persistent high titer or more increasing pattern of CRP after postoperative 3 day or abnormal high titer of CRP after 11 day postoperatively, infection may be highly suspicious.
Alternative Title
The Changes in the Rate of C-Reactive Protein in Orthopaedic Surgery
Keimyung Author(s)(Kor)
송광순
강철형
민병우
Publisher
School of Medicine
Citation
송광순 et al. (1997). 정형외과 수술에 따른 C-reactive protein의 변화. 대한정형외과학회지, 32(3), 697–703.
Type
Article
ISSN
1226-2102
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39548
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.