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저혈당성 뇌병증의 예후 인자에 대한 고찰

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Author(s)
서익권최우익진상찬장혁원
Keimyung Author(s)
Choi, Woo IkJin, Sang ChanChang, Hyuk Won
Department
Dept. of Emergency Medicine (응급의학)
Dept. of Radiology (영상의학)
Journal Title
대한중환자의학회지
Issued Date
2012
Volume
27
Issue
4
Keyword
Diffusion weighted imagingHypoglycemiaPrognosis
Abstract
Background: Recently, there are many reports about the association of Diffusion Weighted Imaging (DWI) and
the prognosis of hypoglycemic encephalopathy (HE), but those relationships have not yet been completely determined.
As such, we researched for prognosis, according to a variety of clinical data, and the lesion’s distribution on DWI.
Methods: We retrospectively reviewed 19 patients who were diagnosed as HE. In addition, those prognoses were
analyzed by a variety of clinical data and characteristics of lesion’s distribution, which were evaluated on DWI and
Apparent Diffusion Coefficient (ADC) maps. Three months later, those prognoses were determined by each Modified
Rankin Scale. Further, the time-dependent average Glasgow Coma Scale (GCS), among the groups according to the
characteristics of lesion‘s distributions in the initial DWI, was estimated.
Results: In this study, the difference of prognosis was not shown, according to all the clinical data, such as the
severity or duration of the hypoglycemic state, but the group that did not have any pathologic lesion on the initial
DWI demonstrated a better prognosis, in comparison with the groups-that exhibited any positive lesion on the initial
DWI (p = 0.006). The group that had a focal pathologic lesion on the initial DWI showed a better prognosis than
the diffuse lesion’s group (p = 0.045). The groups with no lesion or focal lesion showed a faster recovery of GCS
than the other groups with a positive lesion or diffuse lesion within the initial 1 week.
Conclusions: We can identify that the characteristics of the lesion’s distribution of DWI can be more helpful to
predict of prognosis in HE than a variety of clinical data, such as the severity or duration of the hypoglycemic
state.
Alternative Title
Consideration of Prognostic Factors in Hypoglycemic Encephalopathy
Keimyung Author(s)(Kor)
최우익
진상찬
장혁원
Publisher
School of Medicine
Citation
서익권 et al. (2012). 저혈당성 뇌병증의 예후 인자에 대한 고찰. 대한중환자의학회지, 27(4), 209–217. doi: 10.4266/kjccm.2012.27.4.209
Type
Article
ISSN
1229-4802
DOI
10.4266/kjccm.2012.27.4.209
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39632
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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