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수포성 전신성 홍반성 루푸스 1예

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Author(s)
공수득구본식김병천이규석
Keimyung Author(s)
Kim, Byung ChunLee, Kyu Suk
Department
Dept. of Dermatology (피부과학)
Journal Title
대한피부과학회지
Issued Date
1997
Volume
35
Issue
3
Keyword
Systemic lupus erythematosusVesiculobullous eruptionElectronmicroscopy
Abstract
Vesiculobullous eruptions are a rare cutaneous manifestation of systemic lupus erythematosus (SLE). They are related to intense inflammation within the cutaneous lesions and subsequent blister formation. We report a case of vesiculobullous eruption of SLE in a 23-year-old male. The bullous eruptions were present ori the lip, forehead, both feet and hands. He met ARA(American Rheumatism Association) is criteria for a diagnosis of SLE and the eruptions developed during a systemic attack of the disease. Routine histology of the lesion showed subepidermal blisters with intact epidermis and dense neutrophilic infiltration in the upper dermis. Direct immunofluorescence of lesional skin showed a linear-granular pattern of immune deposits at the dermoepidermal junction. Electronmicroscopy of the lesional skin showing subepidermal bullae are located beneath the lamina densa. Combination therapy of prednisolone and hydrochloroquine showed complete clearing of the lesions within several weeks. We observed a good response without evidence of recurrence.
Alternative Title
A Case of Bullous Systemic Lupus Erythematosus
Keimyung Author(s)(Kor)
김병천
이규석
Publisher
School of Medicine
Citation
공수득 et al. (1997). 수포성 전신성 홍반성 루푸스 1예. 대한피부과학회지, 35(3), 588–592.
Type
Article
ISSN
0494-4739
Source
http://kiss.kstudy.com/thesis/thesis-view.asp?key=1871824
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39840
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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