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아토피 피부염 학회 보고서: 한국 소아형 아토피 피부염의 임상적 특징에 대한 연구

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Author(s)
정수진김규한김도원김성진김인주김창욱나건연노영석박건박동재박천욱윤숙정원영호이규석이광훈이승철이원주이애영이정덕장재원장효찬정병수정현최종수최지호허창운조상현
Keimyung Author(s)
Kim, Chang WookLee, Kyu Suk
Department
Dept. of Dermatology (피부과학)
Journal Title
대한피부과학회지
Issued Date
2005
Volume
43
Issue
11
Keyword
Aggravating factorsAtopic dermatitisEczema Area and Severity IndexPrick test
Abstract
BACKGROUND: Atopic dermatitis (AD) is a chronic, relapsing disease with genetic and environmental background. Many factors may act as triggers and affect the course of the disease. However, little is known about the factors affecting the disease severities in Korean childhood AD. OBJECTIVE: The aim was to document the distinct characteristics of childhood AD in Korea and to determine which manifestations are prone to be present in the settings of different severity of the disease. METHOD: The clinical manifestations, past medical and family history, and inducing or aggravating factors were studied in patients, who participated in the open lectures for childhood AD patients in three provinces of Korea. The severity of the disease was evaluated using the Eczema Area and Severity Index (EASI) and the factors affecting the severity of the disease were determined. Skin prick tests with four allergens, Dermatophagoides pteronyssinus, milk, peanut and egg, were also carried out. RESULTS: Of the 93 patients, 38.7% had the disease onset between the age of three and six, while 17.2% had it between the age of seven and fifteen. Sixty-five percent of the patients had family members with a history of atopic diseases, such as AD, asthma, allergic rhinitis and allergic conjunctivitis. In order of frequency, the patients either had a history of or presently accompanying infantile eczema, allergic rhinitis, asthma or allergic conjunctivitis. Among the patients, 27% took herbal medication. The most frequently involved site was the flexural area. The most common aggravating factors were sweating in hot environment, wool fabric and stress. When AD patients were categorized into mild, moderate and severe groups by EASI, the older onset age, the longer duration, facial distribution, history of taking herbal medication, cholinergic condition, wool fabric and stress were found to be significant factors influencing the severity of the disease. Skin prick test with the four major allergens revealed the highest prevalence in Dermatophagoides pteronyssinus. CONCLUSION: The age of onset of AD was higher than that has been reported. Many suffered from infantile dermatitis and had other accompanying atopic diseases. Aggravating factors should be avoided to minimize the risk of disease aggravation. Based on the fact that late onset age, duration, facial distribution, history of taking herbal medication, cholinergic condition, wool and stress were the statistically significant factors, we may predict the severity or the course of the disease.
Alternative Title
Report from ADRG: A Study on the Clinical Manifestations of Childhood Atopic Dermatitis in Korea
Keimyung Author(s)(Kor)
김창욱
이규석
Publisher
School of Medicine
Citation
정수진 et al. (2005). 아토피 피부염 학회 보고서: 한국 소아형 아토피 피부염의 임상적 특징에 대한 연구. 대한피부과학회지, 43(11), 1497–1509.
Type
Article
ISSN
0494-4739
Source
http://kiss.kstudy.com/thesis/thesis-view.asp?key=2486281
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39844
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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