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아토피피부염 환아에서 전신적인 피부 발진의 임상양상을 보인 혈구탐식증후군 1예

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Author(s)
박수정송현정김창욱이규석
Keimyung Author(s)
Kim, Chang WookLee, Kyu Suk
Department
Dept. of Dermatology (피부과학)
Journal Title
대한피부과학회지
Issued Date
2006
Volume
44
Issue
4
Keyword
Hemophagocytic macrophageHemophagocytic syndrome
Abstract
We report a case of 15-year-old patient, previously diagnosed with atopic dermatitis, who presented with generalized erythematous purpuric patches and petechiae on the face, trunk and extremities. The skin lesions appeared 7
days prior to presentation, accompaied by a high grade fever (38.9oC). The lesions had rapidly become aggrevated after an upper respiratory infection, resulting in severe itching sensation. On physical examination, epatosplenomegly
and cervical lymphadenopathy were noted. The laboratory test showed marked pancytopenia, elevated liver enzymes, hypertriglyceridemia, elevated lactic dehydrogenase level and increased ferritin level. Many hemophagocytic
macrophages were detected in bone marrow biopsy. A skin biopsy revealed panniculitis composed of histiocytes and lymphocytes. Hemophagocytic syndrome was diagnosed, and treatment with combination chemotherapy
resulted in complete remission.
Alternative Title
A Case of Hemophagocytic Syndrome Manifested as Generalized
Skin Eruption in Childhood Atopic Dermatitis
Keimyung Author(s)(Kor)
김창욱
이규석
Publisher
School of Medicine
Citation
박수정 et al. (2006). 아토피피부염 환아에서 전신적인 피부 발진의 임상양상을 보인 혈구탐식증후군 1예. 대한피부과학회지, 44(4), 470–473.
Type
Article
ISSN
0494-4739
Source
http://kiss.kstudy.com/thesis/thesis-view.asp?key=2518703
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39845
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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