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심폐소생술시 Isosorbide Dinitrate(Isoket®)가 관상 동맥 관류압에 미치는 효과

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Author(s)
전재규장영호김진모천범수Jae Kyu CbeunYoung Ho JangJin Mo KimBum Soo Cheun
Keimyung Author(s)
Cheun, Jae KyuJang, Young HoKim, Jin Mo
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
대한마취과학회지
Issued Date
1998
Volume
35
Issue
2
Abstract
Background: Coronary perfusion pressure(CPP) is the most important factor for the success of cardiopulmonary resuscitation(CPR). Therefore, CPP must be optimized during the resuscitation. The purpose of this study is to investigate the effects of isosorbide dinitrate(Isoket®) on CPP during OPR.
Methods: 10 Korean dogs were divided into two groups: Group I(N»-5) was resuscitated with infusion of isosorbide dinitrate(l jug /kg/min) and Group II(N-5) was resuscitated without using isosorbide dinitrate. Following CPR, the heart rate(HR), blood pressure(BP), pulmonary capillary wedge pressure, cardiac output(CO),CPP and endocardial viability ratio(EVR) were measured repeatedly.
Results: Hie changes in HR were not significantly different between the two groups but systolic and diastolic BP, CO, CPP and EVR were well maintained in group 1.
ConciusioDS: Hiese results suggest that the usual dosage of isosorbide dinitrate is effective in improving CPP and EVR on CPR after intending cardiac arrest. (Korean J Anesthesiol 1998; 35: 252〜258
Alternative Title
Effects of Isosorbide Dinitrate(Isoket®) on Coronary Perfusion Pressure during the Cardiopulmonary Resuscitation
Keimyung Author(s)(Kor)
전재규
장영호
김진모
Publisher
School of Medicine
Citation
전재규 et al. (1998). 심폐소생술시 Isosorbide Dinitrate(Isoket®)가 관상 동맥 관류압에 미치는 효과. 대한마취과학회지, 35(2), 252–258. doi: 10.4097/kjae.1998.35.2.252
Type
Article
ISSN
0302-5780
DOI
10.4097/kjae.1998.35.2.252
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/40085
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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