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복강경하 담낭 절제술 시 대용량의 수액 투여는 Ondansetron의 효과와 동일하게 수술 후 오심 및 구토를 감소시킨다

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Author(s)
이용철김진모이동열Yong Cheol LeeJin Mo KimDong Yeol Lee
Keimyung Author(s)
Lee, Yong CheolKim, Jin Mo
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
대한마취과학회지
Issued Date
2009
Volume
56
Issue
4
Abstract
Background: The possibility that large fluid volumes reduce postoperative nausea and vomiting (PONV) remains unclear due to conflicting data. We examined if administering large fluid volumes to high risk patients would decrease the incidence of PONV and compared the results with ondansetron administration.
Methods: Ninety ASA I, II patients who presented for laparoscopic cholecystectomy were randomized to 1 of 3 groups. They received either (group I) 5 ml/kg/hr of Hartmann's solution, (group II) 30 ml/kg/hr of Hartmann's solution or (group III) 4 mg of ondansetron and 5 ml/kg/hr of Hartmann's solution. The incidence of PONV and severity of pain were assessed at 1, 12 and 24 hours postoperatively.
Results: The number of PONV episodes was significantly reduced in group II and III compared to group I during the 1−12 hr postoperative period and for total incidence. However, there was no significant difference between group II and III. There were no differences among groups regarding the severity of pain.
Conclusions: Intraoperative correction of intravascular volume deficits with 30 ml/kg/hr of Hartmann's solution decreases the incidence of PONV as effectively as administration of ondansetron. (Korean J Anesthesiol 2009; 56: 403~7)
Key Words: Fluid, Laparoscopic cholecystectomy, Ondansetron, PONV.
Alternative Title
Administration of large fluid volumes decreases the incidence of postoperative nausea and
vomiting as effectively as ondansetron
Keimyung Author(s)(Kor)
이용철
김진모
Publisher
School of Medicine
Citation
이용철 et al. (2009). 복강경하 담낭 절제술 시 대용량의 수액 투여는 Ondansetron의 효과와 동일하게 수술 후 오심 및 구토를 감소시킨다. 대한마취과학회지, 56(4), 403–407. doi: 10.4097/kjae.2009.56.4.403
Type
Article
ISSN
0302-5780
DOI
10.4097/kjae.2009.56.4.403
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/40126
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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