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체외순환 없는 관상동맥우회술시 고혈압 조절을 위한 Nicardipine의 혈역학적 반응

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Author(s)
김성기박태규신원호장영호김진모김애라전재규Seong Ki KimTae Kyu ParkWon Ho SinYoung Ho JangJin Mo KimAe Ra KimJae Kyu Cheun
Keimyung Author(s)
Jang, Young HoKim, Jin MoKim, Ae RaCheun, Jae Kyu
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
대한마취과학회지
Issued Date
2001
Volume
41
Issue
2
Abstract
Drugs for acute blood pressure control are often required during a cardiovascular operation. Hypertension frequently occurs in an off-pump coronary artery bypass graft. The purpose of this study was to evaluate the effect of nicardipine on hemodynamic change.
Twenty adult patients were studied. Anesthesia was induced intravenously with thiopental (4 mg/kg), vecuronium (1 mg/kg), and fentanyl (4μg/kg), and maintained with 100% O2 and isoflurane 1⁣1.5 Vol%. When systolic blood pressure rose above 150 mmHg, nicardipine 1 mg was administrated intravenously. Immediately after the nicardipine bolus injection, nicardipine was infused continuously 0.5⁣4μg/kg/min. Thereafter, hemodynamic data was recorded.
Systolic blood pressure decreased, but cardiac index significantly increased after an intravenous administration of nicardipine and was maintained during the study. There was no incidence of tachycardia.
It was concluded that acute blood pressure control using nicardipine could be suitable and safe in patients with an off-pump CABG. (Korean J Anesthesiol 2001; 41: 171∼177)
Keyword : Blood pressure hypertension. Heart hemodynamics; nicardipine.
Alternative Title
The Hemodynamic Response of Nicardipine for Hypertension Control during an Off-Pump Coronary Artery Bypass Graft
Keimyung Author(s)(Kor)
장영호
김진모
김애라
전재규
Publisher
School of Medicine
Citation
김성기 et al. (2001). 체외순환 없는 관상동맥우회술시 고혈압 조절을 위한 Nicardipine의 혈역학적 반응. 대한마취과학회지, 41(2), 171~177-171~177. doi: 10.4097/kjae.2001.41.2.171
Type
Article
ISSN
0302-5780
DOI
10.4097/kjae.2001.41.2.171
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/40130
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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