계명대학교 의학도서관 Repository

혈역학적으로 불안정한 환자에서 마취유도전 Fentanyl, Lidocaine, Esmolol 정주후 기관내 삽관시 혈역학적 변화

Metadata Downloads
Author(s)
박은지곽민전이정구정정길Eun Jee ParkMin Jeon KwagJung Koo LeeJung Kil Chung
Keimyung Author(s)
Lee, Jung KooChung, Jung Kil
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
대한마취과학회지
Issued Date
1998
Volume
35
Issue
1
Abstract
Background: Tracheal intubation is accompanied by varing degrees of sympathetic stimulation as reflected by increases in heart rate, and blood pressure and several clinical trials to reduce the effects on blood pressure and heart rate by pharmacologic agents such as α and β blockers, calcicum channel blockers, narcotics and lidocaine, have been reported.
Methods: To evaluate the effect of fentanyl, lidocaine, esmolol on the hemodynamic changes induced by intubation, we administered thiopental 5 mg/kg only (group 1, n=12), fentanyl 2 μg/kg with thiopental 5 mg/kg (group 2, n=12), lidocaine 1 mg/kg with thiopental 5 mg/kg group 3, n=12) or esmolol 0.5 mg/kg with thiopental 5 mg/kg (group 4, n=12) for induction of anesthesia, and measured heart rate, systolic blood pressure, diastolic blood pressure, mean arteiral pressure, and rate-pressure products (RPP) before induction, after induction, after intubation and at 1, 2, 3, and 5 minutes after intubation.
Results: There was a significant increase in heart rate, systolic blood pressure and RPP after intubation and 1 min after intubation in all groups, but in group 2, group 3 and group 4, the cardiovascular responses were more attenuated compared to group 1.
Conclusion: The preintubation intravenous injection of fentanyl, lidocaine and esmolol may offer important roles in the hemodynamically unstable patients because it attenuate cardiovascular responses with intubation. (Korean J Anesthesiol 1998; 35: 50∼57)
Key word : Intubation, tracheal : sympathetic stimulation. Pharmacology : fentanyl; lidocaine; esmolol.
Alternative Title
A Comparison of Fentanyl, Lidocaine and Esmolol for Blunting the Hemodynamic Response during Rapid-Sequence Induction in the Hemodynamically Unstable Patients
Keimyung Author(s)(Kor)
이정구
정정길
Publisher
School of Medicine
Citation
박은지 et al. (1998). 혈역학적으로 불안정한 환자에서 마취유도전 Fentanyl, Lidocaine, Esmolol 정주후 기관내 삽관시 혈역학적 변화. 대한마취과학회지, 35(1), 50–57. doi: 10.4097/kjae.1998.35.1.50
Type
Article
ISSN
0302-5780
DOI
10.4097/kjae.1998.35.1.50
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/40137
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.