임상가검물에서 분리된 Klebsiella species의 항균제 감수성

Abstract

One hundred and two Klebsiella species isolated from various clinical specimens in Taegu area were tested for antimicrobial drug susceptibility to 20 drugs including 6 drugs of quinolones, 5 of beta-lactam antibiotics, 5 of aminoglycosides, and other 5 drugs. Klebsiella species were most frequently isolated from urine(67.8%), and followed by sputum(11.8%), pus(4.9%) and etc. All stranins were susceptible to enoxacin(Ex), norfloxacin (Nf), ciprofloxacin (Cp), ofloxacin (Of), pefloxacin(Pf) and moxalactam(Mx). 2.9-15.7% of the strains were resistant to nalidixic acid(Na), amikacin (Ak) and rifampin (Rf), and 24.5-38.2% were resistant to cephalothin, cef amandole (Cf), streptomycin, kanamycin, gentamicin, tobramycin (To), chloramphenicol and trimethoprim. 50-97.1% of the strains were resistant to ampicillin, tetracyclin, sulfisᄋmidine. MIC90 of Ex, Nf, Cp, Of, Pf and Mx were below the antimicrobial drug concentration tested. MIC90 of Na, Cf, Ak, To and Rf were 3.83-91.02^g/ml and those of other drugs were 224.71- >2048/μg/mL Of 102 strains tested, 30 strains were multiply resistant to 8 or more drugs. Key Words: Antimicrobial resistance, Klebsiella species.