계명대학교 의학도서관 Repository

고유량 비강 산소 요법 치료의 실패를 응급실 내원 초기에 예측할 수 있는 인자

Metadata Downloads
Author(s)
은승완김태권전재천최우익진상찬
Keimyung Author(s)
Jeon, Jae CheonJin, Sang ChanChoi, Woo Ik
Department
Dept. of Emergency Medicine (응급의학)
Journal Title
Keimyung Medical Journal
Issued Date
2018
Volume
37
Issue
2
Keyword
High flow nasal cannulaOxygen therapyRespiratory failure
Abstract
High flow nasal cannula (HFNC) oxygen therapy has become a substitute
for other non-invasive ventilation (NIV) and mechanical ventilation in
patients with respiratory failure. Despite its strong points, HFNC may
result in failure of therapy, and delayed intubation leads to poor patient
outcomes. This study is aimed to identify the variables that predicts HFNC
oxygen therapy failure in order to increment success rate and prevent
delayed intubation. The study was conducted in a retrospective manner,
enrolling all non-traumatic patients over the age 20 who visited a single
university-affiliated tertiary medical center emergency room and were
treated with HFNC between March 1, 2016 to Feburary 28, 2017. Patients
were classified into two groups: HFNC success group, and HFNC failure
group: HFNC failure group was defined as patients who were treated with
HFNC, and resulted in intubation and mechanical ventilation, or death.
General characteristics, clinical features, and laboratory findings of the two
groups were compared. Additionally, univariable logistic regression was
done for statistically significant variables, and if the p -value was <0.05,
multivariable logistic regression analysis was conducted. 95 patients were
enrolled in the study. Repeated-measure ANOVA was conducted for serial
arterial blood gas samples during therapy. 62 patients were successful in
the treatment, and the treatment failed in 33 cases. After multivariate
logistic regression analysis, variable that showed statistically significant
association with HFNC failure was initial hematocrits (p < 0.05).
Repeated-measure ANOVA revealed low bicarbonate as a predictor of
HFNC failure. Predictors of HFNC therapy failure are
initial hematocrits, bicarbonate levels during therapy.
Alternative Title
Early Predictors of High-Flow Nasal Cannula Oxygen Therapy Failure in the
Emergency Room
Keimyung Author(s)(Kor)
전재천
진상찬
최우익
Publisher
Keimyung University School of Medicine
Citation
은승완 et al. (2018). 고유량 비강 산소 요법 치료의 실패를 응급실 내원 초기에 예측할 수 있는 인자. Keimyung Medical Journal, 37(2), 66-75-66–75.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/40363
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2018
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.