계명대학교 의학도서관 Repository

Comparison of anatomic and non-anatomic hepatic resection for hepatocellular carcinoma

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Author(s)
Masaki KaiboriMasanori KonTomoki KitawakiTakayuki KawauraKiyoshi HasegawaNorihiro KokudoShunichi AriizumiToru BeppuHiroyuki IshizuShoji KuboToshiya KamiyamaHiroyuki TakamuraTsuyoshi KobayashiDong-Sik KimHee Jung WangJong Man KimDai Hoon HanSang-Jae ParkKoo Jeong KangShin HwangYounghoon RohYoung Kyung YouJae-Won JohMasakazu Yamamoto
Keimyung Author(s)
Kang, Koo Jeong
Department
Dept. of Surgery (외과학)
Journal Title
Journal of Hepato-Biliary-Pancreatic Sciences
Issued Date
2017
Volume
24
Issue
11
Keyword
Anatomic resectionHepatocellular carcinomaNon‐anatomic resectionOverall survival
Abstract
Background:
The aim of the present study was to compare the prognostic impact of anatomic resection (AR) versus non‐anatomic resection (NAR) on patient survival after resection of a single hepatocellular carcinoma (HCC).

Methods:
To control for confounding variable distributions, a 1‐to‐1 propensity score match was applied to compare the outcomes of AR and NAR. Among 710 patients with a primary, solitary HCC of <5.0 cm in diameter that was resectable by either AR or NAR from 2003 to 2007 in Japan and Korea, 355 patients underwent NAR and 355 underwent AR of at least one section with complete removal of the portal territory containing the tumor.

Results:
Overall survival (OS) was better in the AR than NAR group (hazard ratio 1.67, 95% confidence interval 1.28–2.19, P < 0.001) while disease‐free survival showed no significant difference. Significantly fewer patients in the AR than NAR group developed intrahepatic HCC recurrence and multiple intrahepatic recurrences. Patients with poorly differentiated HCC who underwent AR had improved disease‐free survival and OS.

Conclusions:
Anatomic resection decreases the risk of tumor recurrence and improves OS in patients with a primary, solitary HCC of <5.0 cm in diameter.
Keimyung Author(s)(Kor)
강구정
Publisher
School of Medicine (의과대학)
Citation
Masaki Kaibori et al. (2017). Comparison of anatomic and non-anatomic hepatic resection for hepatocellular carcinoma. Journal of Hepato-Biliary-Pancreatic Sciences, 24(11), 616–626. doi: 10.1002/jhbp.502
Type
Article
ISSN
1868-6974
DOI
10.1002/jhbp.502
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41021
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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