계명대학교 의학도서관 Repository

Comparison of drug-eluting stents and drug-coated balloon for the treatment of drug-eluting coronary stent restenosis: A randomized RESTORE trial

Metadata Downloads
Author(s)
Yiu Tung AnthonyWongDo-YoonKangJinBae LeeSeung-WoonRhaYoung JoonHongEun-Seok ShinSung-Ho HerChang Wook NamWoo-Young ChungMoo Hyun KimCheol Hyun LeePil Hyung LeeJung-Min AhnSoo-Jin KangSeung-Whan LeeYoung-HakKimCheolWhan LeeSeong-Wook ParkDuk-WooParkSeung-JungPark
Keimyung Author(s)
Nam, Chang Wook
Department
Dept. of Internal Medicine (내과학)
Journal Title
American Heart Journal.
Issued Date
2018
Volume
197
Abstract
BACKGROUND:

This study sought to evaluate the optimal treatment for in-stent restenosis (ISR) of drug-eluting stents (DESs).

METHODS:

This is a prospective, multicenter, open-label, randomized study comparing the use of drug-eluting balloon (DEB) versus second-generation everolimus-eluting stent for the treatment of DES ISR. The primary end point was in-segment late loss at 9-month routine angiographic follow-up.

RESULTS:

A total of 172 patients were enrolled, and 74 (43.0%) patients underwent the angiographic follow-up. The primary end point was not different between the 2 treatment groups (DEB group 0.15±0.49 mm vs DES group 0.19±0.41 mm, P=.54). The secondary end points of in-segment minimal luminal diameter (MLD) (1.80±0.69 mm vs 2.09±0.46 mm, P=.03), in-stent MLD (1.90±0.71 mm vs 2.29±0.48 mm, P=.005), in-segment percent diameter stenosis (34%±21% vs 26%±15%, P=.05), and in-stent percent diameter stenosis (33%±21% vs 21%±15%, P=.002) were more favorable in the DES group. The composite of death, myocardial infarction, or target lesion revascularization at 1 year was comparable between the 2 groups (DEB group 7.0% vs DES group 4.7%, P=.51).

CONCLUSIONS:

Treatment of DES ISR using DEB or second-generation DES did not differ in terms of late loss at 9-month angiographic follow-up, whereas DES showed better angiographic results regarding minimal MLD and percent diameter stenosis. Both treatment strategies were safe and effective up to 1year after the procedure.
Keimyung Author(s)(Kor)
남창욱
Publisher
School of Medicine (의과대학)
Citation
Yiu Tung AnthonyWong et al. (2018). Comparison of drug-eluting stents and drug-coated balloon for the treatment of drug-eluting coronary stent restenosis: A randomized RESTORE trial. American Heart Journal., 197, 35–42. doi: 10.1016/j.ahj.2017.11.008
Type
Article
ISSN
0002-8703
Source
https://linkinghub.elsevier.com/retrieve/pii/S0002-8703(17)30364-2
DOI
10.1016/j.ahj.2017.11.008
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41146
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.