계명대학교 의학도서관 Repository

Comparison of long-term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug-eluting stents

Metadata Downloads
Author(s)
Ki-Bum WonHyuck-Jun YoonSang-Gon LeeYun-Kyeong ChoChang-Wook NamSeung-Ho HurSeung-Whan LeePil-Hyung LeeJung-Min AhnDuk-Woo ParkSoo-Jin KangYoung-Hak KimCheol-Whan LeeSeong-Wook ParkSeung-Jung Park
Keimyung Author(s)
Hur, Seung HoNam, Chang WookCho, Yun KyeongYoon, Hyuck Jun
Department
Dept. of Internal Medicine (내과학)
Journal Title
Catheterization and Cardiovascular Interventions
Issued Date
2018
Volume
91
Issue
4
Keyword
chronic total occlusiondrug-eluting stentmortalityobesity
Abstract
OBJECTIVE:

To evaluate the long-term mortality according to obesity in patients with chronic total occlusion (CTO) lesions after successful percutaneous coronary intervention (PCI).

BACKGROUND:

Despite the potential impact of coronary revascularization and lesion severity on the obesity paradox, the long-term survival according to obesity in CTO patients after successful PCI has been unknown.

METHODS AND RESULTS:

Between January 2003 and September 2014, we examined 1,172 consecutive Korean patients with 1,190 CTO lesions who underwent successful drug-eluting stent (DES) implantation in two tertiary academic medical centers. The primary and secondary endpoints were all-cause and cardiac death, respectively. Obesity was defined as a body mass index ≥25.0 kg/m2 , based on the criteria for Asians. The median follow-up time was 4.4 years. The prevalence of obesity was 54.4%. During the follow-up periods, the occurrence of all-cause (6.1 vs. 10.7%) and cardiac death (3.8 vs. 6.7%) was lower in obese patients than in non-obese patients (P <0.05, respectively). Kaplan-Meier analysis showed that obese patients had lower cumulative rates of all-cause and cardiac death than did non-obese patients (log-rank P <0.05, respectively). Univariate Cox regression analysis showed that age ≥65 years (hazard ratio [HR], 3.62), diabetes mellitus (HR, 1.94), renal dysfunction (HR, 7.03), systolic heart failure (HR, 2.61), and obesity (HR, 0.58) were associated with all-cause death (P <0.05). Multivariate Cox regression models showed that high BMI was independently associated with the decreased risk of all-cause death.

CONCLUSIONS:

Obese patients appear to have a lower long-term mortality than do non-obese patients in CTO after successful PCI using DES. © 2017 Wiley Periodicals, Inc.
Keimyung Author(s)(Kor)
허승호
남창욱
조윤경
윤혁준
Publisher
School of Medicine (의과대학)
Citation
Ki-Bum Won et al. (2018). Comparison of long-term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug-eluting stents. Catheterization and Cardiovascular Interventions, 91(4), 710–716. doi: 10.1002/ccd.27110
Type
Article
ISSN
1522-1946
Source
https://onlinelibrary.wiley.com/doi/full/10.1002/ccd.27110
DOI
10.1002/ccd.27110
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41152
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Authorize & License
  • Authorize공개
  • EmbargoForever
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.