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Dronedarone에 의해 발생한 광과민성피부염 1예

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Author(s)
이지호김소민정창규박해심신유섭
Keimyung Author(s)
Jung, Chang Gyu
Department
Dept. of Internal Medicine (내과학)
Journal Title
Allergy Asthma & Respiratory Disease
Issued Date
2017
Volume
5
Issue
6
Keyword
DronedaronePhotosensitivityPhotopatch test
Abstract
Dronedarone is a new antiarrhythmic drug for the treatment of nonpermanent atrial fibrillation. Compared with amiodarone, it is regarded as a safe medication due to its structural differences. In this report, we describe a 56-year-old man who developed photo sensitivity due to dronedarone. He presented with itchy skin rashes for 1 week. Maculopapular exanthema was localized on the neck, both arms, and both hands, with sparing of the other parts of the body. Dronedarone was prescribed 4 weeks ago when atrial fibrillation occurred. After development of skin rashes, dronedarone was discontinued, and systemic steroid, antihistamine, and topical corticosteroid were administered for 1 week, with improvement in skin rashes. The photopatch test was performed with an tiarrhythmic drugs, including dronedarone, amiodarone, and flecainide, 4 weeks after withdrawal of dronedarone. Positive reactions were recorded only to dronedarone at the site exposed to ultraviolet A. He was diagnosed with dronedarone-induced photosensi tivity and advised to change the antiarrhythmic medication to others. There have been a few case reports on photosensitivity reac tions due to dronedarone, which were diagnosed only by clinical suspicion. However, we suspected photosensitivity and proved it by the photopatch test. Photosensitivity should be considered in patients having skin rashes on the exposed area and taking antiar rhythmic medication, including dronedarone. (Allergy Asthma Respir Dis 2017;5:358-360)
Alternative Title
Photosensitivity caused by dronedarone: A case report
Keimyung Author(s)(Kor)
정창규
Publisher
School of Medicine (의과대학)
Citation
이지호 et al. (2017). Dronedarone에 의해 발생한 광과민성피부염 1예. Allergy Asthma & Respiratory Disease, 5(6), 358–360. doi: 10.4168/aard.2017.5.6.358
Type
Article
ISSN
2288-0402
DOI
10.4168/aard.2017.5.6.358
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41200
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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