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Effect of Two Different Doses of Intravitreal Bevacizumab with Temporal Retina-Sparing Laser Photocoagulation for Retinopathy of Prematurity

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Author(s)
A Young ChoiHochan ChoYu Cheol Kim
Keimyung Author(s)
Kim, Yu CheolCho, Ho Chan
Department
Dept. of Ophthalmology (안과학)
Dept. of Internal Medicine (내과학)
Journal Title
International Journal of Ophthalmology
Issued Date
2018
Volume
11
Issue
1
Keyword
bevacizumablaser photocoagulationretinopathy of prematurity
Abstract
This study aims to compare the efficacy and safety between two different doses of intravitreal bevacizumab (IVB) injection with temporal retina-sparing laser (TRSL) photocoagulation for retinopathy of prematurity (ROP). We retrospectively evaluated 22 eyes of ROP infants who underwent IVB combined with partial TRSL for stage 3+ zone I or posterior zone II ROP. Laser photocoagulation was applied on the avascular retina, sparing two-disc-diameter width temporal avascular area anterior to ridge. A half dose (0.625 mg) or minimal dose (0.25 mg) of IVB was conducted. Four eyes in minimal dose group were retreated with IVB and laser photocoagulation on the spared retina. Of those 4 retreated eyes, three developed preretinal hemorrhage around the ridge after the first treatment, resulting in fibrotic macular dragging. A half dose of IVB may be more effective than a minimal dose with partial TRSL for ROP. Preretinal hemorrhage may be a harbinger of poor prognosis.
Keimyung Author(s)(Kor)
김유철
조호찬
Publisher
School of Medicine (의과대학)
Citation
A Young Choi et al. (2018). Effect of Two Different Doses of Intravitreal Bevacizumab with Temporal Retina-Sparing Laser Photocoagulation for Retinopathy of Prematurity. International Journal of Ophthalmology, 11(1), 166–169. doi: 10.18240/ijo.2018.01.26
Type
Article
ISSN
2222-3959
DOI
10.18240/ijo.2018.01.26
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41209
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
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