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Efficacy of ketamine for postoperative pain following robotic thyroidectomy: A prospective randomised study

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Author(s)
Jiwon LeeHee-Pyoung ParkMu-Hui JeongJe-Do SonHyun-Chang Kim
Keimyung Author(s)
Son, Je DoKim, Hyun ChangLee, Ji Won
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
Journal of International Medical Research
Issued Date
2018
Volume
46
Issue
3
Keyword
Ketamineminimally invasive surgical procedurespainpercutaneous tunnelingpostoperativethyroidectomy
Abstract
Objective Although robotic thyroidectomy (RoT) is a minimally invasive surgery, percutaneous tunneling causes moderate to severe pain immediately postoperatively. We evaluated the efficacy of ketamine for postoperative pain management in patients following RoT. Methods Sixty-four patients scheduled for RoT were randomly divided into two groups. In the ketamine group (n = 32), ketamine was infused from induction of anaesthesia until the end of the procedure (0.15-mg/kg bolus with continuous infusion at 2 µg/kg/min). In the control group (n = 32), the same volume of saline was infused. Visual analogue scale (VAS) scores for acute and chronic pain, the incidence of hypoesthesia, postoperative analgesic requirements, and complications related to opioids or ketamine were compared between the two groups. Results The VAS pain scores were significantly lower in the ketamine group up to 24 h postoperatively. The VAS pain score when coughing was significantly higher in the control group than in the ketamine group at 24 h postoperatively. A significantly greater proportion of patients in the control group required rescue analgesics. Complications were comparable in both groups. Conclusions Ketamine infusion decreased pain scores for 24 h postoperatively and reduced analgesic requirements without serious complications in patients following RoT.
Keimyung Author(s)(Kor)
김현창
이지원
손제도
Publisher
School of Medicine (의과대학)
Citation
Jiwon Lee et al. (2018). Efficacy of ketamine for postoperative pain following robotic thyroidectomy: A prospective randomised study. Journal of International Medical Research, 46(3), 1109–1120. doi: 10.1177/0300060517734679
Type
Article
ISSN
0300-0605
DOI
10.1177/0300060517734679
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41232
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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