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Incidence of venous thromboembolism in Korea from 2009 to 2013

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Author(s)
Junshik HongJu Hyun LeeHo-Young YhimWon-Il ChoiSoo-Mee BangHeeyoung LeeDoyeun Oh
Keimyung Author(s)
Choi, Won Il
Department
Dept. of Internal Medicine (내과학)
Journal Title
PLoS One
Issued Date
2018
Volume
13
Issue
1
Abstract
The incidence of venous thromboembolism (VTE) is lower in Asian populations than in Western populations. The objective of the present study was to evaluate the annual age- and sex-adjusted incidence (ASR) of VTE from 2009 to 2013 in South Korea. In addition, annual change in the pattern of VTE treatment during the study period was estimated because a new direct oral anticoagulant (DOAC) had become available and was covered by health insurance in Korea beginning in January 2013. VTE cases from 2009 to 2013 were retrospectively identified based on both diagnostic and medication codes of anticoagulants used for initial treatment using the Korean Health Insurance Review and Assessment Service (HIRA) databases. The incidence of VTE increased yearly. It was significantly higher in the older population than in the younger population, and it was higher in females than in males. In 2009, ASRs of VTE, deep vein thrombosis, and pulmonary embolism were 21.3, 8.1, and 13.2 cases per 100,000 individuals, respectively in 2009. These increased to 29.2, 12.7, and 16.6 cases per 100,000, respectively, in 2013. Prescription rates of warfarin and low-molecular-weight heparin decreased with the introduction of a new anticoagulant in 2013. The proportion of subjects who underwent mechanical procedures decreased annually. The ASR of VTE in Korea continuously increased from 2009 to 2013, reflecting an increased awareness and detection of VTE as well as improved survival of patients with cancer and other morbidities. Following its introduction, DOAC rapidly replaced other anticoagulants for the treatment of VTE.
Keimyung Author(s)(Kor)
최원일
Publisher
School of Medicine (의과대학)
Citation
Junshik Hong et al. (2018). Incidence of venous thromboembolism in Korea from 2009 to 2013. PLoS One, 13(1), e0191897–e0191897. doi: 10.1371/journal.pone.0191897
Type
Article
ISSN
1932-6203
DOI
10.1371/journal.pone.0191897
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41299
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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