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Medication nonadherence in Korean patients with rheumatoid arthritis: the importance of belief about medication and illness perception

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Author(s)
Young Sun SuhYun-Hong CheonHyun-Ok KimRock-Bum KimKi Soo ParkSang-Hyon KimSeung-Geun LeeEun-Kyoung ParkJian HurSang-Il Lee
Keimyung Author(s)
Kim, Sang Hyon
Department
Dept. of Internal Medicine (내과학)
Journal Title
Antirheumatic agents
Arthritis, rheumatoid
Medication adherence
Issued Date
2018
Volume
33
Issue
1
Keyword
Antirheumatic agentsArthritis, rheumatoidMedication adherence
Abstract
BACKGROUND/AIMS:
To investigate medication nonadherence in Korean patients with rheumatoid arthritis (RA) and analyze related factors.

METHODS:
A total of 292 patients with RA participated in this study. Medication nonadherence, intentional or unintentional, was gauged via self-reported questionnaire. Patient perceptions of illness, treatment beliefs, and moods were measured via Brief Illness Perception Questionnaire, Beliefs about Medicines Questionnaire, and Patient Health Questionnaire-2, respectively. Demographic and clinical data were also collected. Multinomial regression analysis was used to assess the impact of demographic, clinical, and psychological factors on medication nonadherence.

RESULTS:
The medication nonadherence rate was 54.1% (intentional, 21.6%; unintentional, 32.5%). Intentional nonadherence was reported most often in patients treated daily drugs (nonsteroidal anti-inflammatory drugs and/or disease-modifying antirheumatic drugs) (24.2%), and unintentional nonadherence was highest in patients receiving methotrexate (33.3%) (p = 0.872). In univariate analysis, beliefs in necessity and concerns of medication differed significantly in adherent and nonadherent patients (intentional or unintentional). When controlling for other factors that may impact medication nonadherence, less belief in necessity of medication (odds ratio [OR], 0.81; 95% confidence interval [CI], 0.68 to 0.95) and greater emotional response to disease (OR, 1.19; 95% CI, 1.01 to 1.40) were important predictors of intentional nonadherence.

CONCLUSIONS:
Medication nonadherence is common in Korean patients with RA. Less belief in necessity of medication and greater emotional response to disease were identified as key factors prompting intentional nonadherence. These factors may be strategically targeted to improve medication adherence rates and subsequent clinical outcomes.
Keimyung Author(s)(Kor)
김상현
Publisher
School of Medicine (의과대학)
Citation
Young Sun Suh et al. (2018). Medication nonadherence in Korean patients with rheumatoid arthritis: the importance of belief about medication and illness perception. Antirheumatic agents, 33(1), 203–210. doi: 10.3904/kjim.2015.383
Type
Article
ISSN
1226-3303
DOI
10.3904/kjim.2015.383
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41346
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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