Optimal Timing of Percutaneous Coronary Intervention in Patients With Non-ST-Segment Elevation Myocardial Infarction Complicated by Acute Decompensated Heart Failure (from the Korea Acute Myocardial Infarction Registry-National Institutes of Health [KAMIR-NIH]).
- Author(s)
- Min Chul Kim; Myung Ho Jeong; Doo Sun Sim; Young Joon Hong; Ju Han Kim; Youngkeun Ahn; Tae Hoon Ahn; Ki Bae Seung; Dong-Joo Choi; Hyo-Soo Kim; Hyeon Cheol Gwon; In Whan Seong; Kyung Kuk Hwang; Shung Chull Chae; Seung Ho Hur; Kwang Soo Cha; Seok Kyu Oh; Jei Keon Chae; KAMIR-NIH registry investigators
- Keimyung Author(s)
- Hur, Seung Ho
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- American Journal of Cardiology
- Issued Date
- 2018
- Volume
- 121
- Issue
- 11
- Abstract
- The optimal timing of percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation myocardial infarction (NSTEMI), complicated by acute decompensated heart failure (ADHF), is unclear. A total of 1,027 patients with NSTEMI complicated by ADHF who underwent successful PCI were analyzed using a Korean multicenter registry. All patients were divided into 4 groups by the timing of PCI: group 1 (PCI < 2 hour after admission, n = 149), group 2 (2 to 24 hours, n = 577), group 3 (24 to 72 hours, n = 189), and group 4 (≥72 hours, n = 112). We analyzed the incidences of 12-month mortality, nonfatal myocardial infarction (MI), target-vessel revascularization, and rehospitalization because of HF. The prevalence of ADHF in patients with NSTEMI was 15.2% at initial presentation, and in-hospital mortality was higher in group 1 than in the other groups. There were no significant differences in mortality, nonfatal MI, target-vessel revascularization, or rehospitalization for HF during the 12-month follow-up between groups, regardless of initial PCI timing, except for a higher 12-month mortality in patients who received PCI within 24 hours (vs ≥24 hours) (hazard ratio 1.52, 95% confidence interval 1.09 to 2.29, p = 0.046). Early PCI did not reduce adverse clinical outcomes in patients with NSTEMI complicated by ADHF. Delayed PCI after stabilization may be reasonable in such high-risk patients.
- Keimyung Author(s)(Kor)
- 허승호
- Publisher
- School of Medicine (의과대학)
- Citation
- Min Chul Kim et al. (2018). Optimal Timing of Percutaneous Coronary Intervention in Patients With Non-ST-Segment Elevation Myocardial Infarction Complicated by Acute Decompensated Heart Failure (from the Korea Acute Myocardial Infarction Registry-National Institutes of Health [KAMIR-NIH]). American Journal of Cardiology, 121(11), 1285–1292. doi: 10.1016/j.amjcard.2018.01.051
- Type
- Article
- ISSN
- 0002-9149
- Source
- https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(18)30240-6
- DOI
- 10.1016/j.amjcard.2018.01.051
- URI
- https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41373
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