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Potential Biomarkers for NSAID-Exacerbated Respiratory Disease

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Author(s)
Hanki ParkYoungwoo ChoiChang-Gyu JungHae-Sim Park
Keimyung Author(s)
Jung, Chang Gyu
Department
Dept. of Internal Medicine (내과학)
Journal Title
Mediators of Inflammation
Issued Date
2017
Volume
2017
Abstract
Asthma is a common chronic disease with several variant phenotypes and endotypes. NSAID-exacerbated respiratory disease (NERD) is one such endotype characterized by asthma, chronic rhinosinusitis (CRS) with nasal polyps, and hypersensitivity to aspirin/cyclooxygenase-1 inhibitors. NERD is more associated with severe asthma than other asthma phenotypes. Regarding diagnosis, aspirin challenge tests via the oral or bronchial route are a standard diagnostic method; reliable in vitro diagnostic tests are not available. Recent studies have reported various biomarkers of phenotype, diagnosis, and prognosis. In this review, we summarized the known potential biomarkers of NERD that are distinct from those of aspirin-tolerant asthma. We also provided an overview of the different NERD subgroups.
Keimyung Author(s)(Kor)
정창규
Publisher
School of Medicine (의과대학)
Citation
Hanki Park et al. (2017). Potential Biomarkers for NSAID-Exacerbated Respiratory Disease. Mediators of Inflammation, 2017, 8160148–8160148. doi: 10.1155/2017/8160148
Type
Article
ISSN
0962-9351
DOI
10.1155/2017/8160148
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41397
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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