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Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score,CRIB II score, initial and lowest serum albumin levels

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Author(s)
Jae Hyun ParkYun Sil ChangSo Yoon AhnSe In SungWon Soon Park
Keimyung Author(s)
Park, Jae Hyun
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
PloS One
Issued Date
2018
Volume
13
Issue
2
Abstract
We explored GA, BW, Apgar score, CRIB II score, and serum albumin levels as univariate predictors of mortality in extremely low birth weight infants. Medical records of 564 extremely low birth weight infants were reviewed retrospectively. The infants were grouped as survivors (group I), expired ≤ 7th postnatal day (group II), and expired > 7th postnatal day (group III). The predictive value for mortality of gestational age, birth weight, Apgar scores at 1 and 5 min, clinical risk index for babies II score, and first and lowest serum albumin levels was assessed by calculating the associated area under the curve (AUC) in receiver operating characteristic (ROC) curves. The overall survival and mortality rates of groups I, II, and III were 81.0% (457/564), 7.6% (43/564), and 11.4% (64/564), respectively. Birth weight, Apgar scores at 1 and 5 min, and first serum albumin levels were significantly higher, while the clinical risk index for babies II score was significantly lower in group I when compared to groups II and III. Gestational age and lowest serum albumin level in group I were significantly higher than group III, but not group II. However, gestational age, birth weight, and clinical risk index for babies II score showed gestational age dependent variations regardless of survival or mortality. Apgar score at 5 min (0.756) and lowest serum albumin level (0.771) demonstrated the highest AUC of the ROC curve in predicting mortality in group II and III, respectively. In conclusion, Apgar score at 5 min and lowest serum albumin level were the most effective predictors for mortality in extremely low birth weight infants during ≤ 7th and > 7th postnatal days, respectively.
Keimyung Author(s)(Kor)
박재현
Publisher
School of Medicine (의과대학)
Citation
Jae Hyun Park et al. (2018). Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score,CRIB II score, initial and lowest serum albumin levels. PloS One, 13(2), e0192232–e0192232. doi: 10.1371/journal.pone.0192232
Type
Article
ISSN
1932-6203
DOI
10.1371/journal.pone.0192232
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41401
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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