계명대학교 의학도서관 Repository

The optimal surgical resection approach for T2 gallbladder carcinoma: evaluating the role of surgical extent according to the tumor location

Metadata Downloads
Author(s)
Tae Jun ParkKeun Soo AhnYong Hoon KimTae-Seok KimJung Hee HongKoo Jeong Kang
Keimyung Author(s)
Ahn, Keun SooKim, Yong HoonKim, Tae SeokKang, Koo Jeong
Department
Dept. of Surgery (외과학)
Journal Title
Annals of Surgical Treatment and Research
Issued Date
2018
Volume
94
Issue
3
Keyword
Gallbladder neoplasmsSurgery
Abstract
Purpose:

The clinical behavior of T2 gallbladder cancer varies among patients. The aims of this study were to identify prognostic factors for survival and recurrence, and to determine the optimal surgical strategy for T2 gallbladder cancer.

Methods:

We conducted a retrospective analysis of 78 patients with T2 gallbladder cancer who underwent surgical resection for gallbladder cancer.

Results:

Twenty-eight patients (35.9%) underwent simple cholecystectomy and 50 (64.1%) underwent extended cholecystectomy. Among 56 patients without LN metastasis (n = 20) or unknown LN status (no LN dissection, n = 36), the 5-year disease-free survival rates were 81.6%, and 69.8% (P = 0.080). In an analysis according to tumor location, patients with tumors located on the hepatic side (n = 36) had a higher recurrence rate than patients with tumors located on the peritoneal side only (n = 35) (P = 0.043). On multivariate analysis, R1 resection and lymph node metastasis were significant, independent prognostic factors for poor disease-free and overall survival.

Conclusion:

R0 resection and LN dissection are an appropriate curative surgical strategy in patients with T2 gallbladder cancer. Tumors located on the hepatic side show worse prognosis than tumors located on the peritoneal side only, hepatic resection should be considered
Keimyung Author(s)(Kor)
강구정
김용훈
안근수
김태석
Publisher
School of Medicine (의과대학)
Citation
Tae Jun Park et al. (2018). The optimal surgical resection approach for T2 gallbladder carcinoma: evaluating the role of surgical extent according to the tumor location. Annals of Surgical Treatment and Research, 94(3), 135–141. doi: 10.4174/astr.2018.94.3.135
Type
Article
ISSN
2288-6575
DOI
10.4174/astr.2018.94.3.135
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41534
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.