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The prevalence and risk factors of functional dyspepsia in health check-up participants: A nationwide multicenter prospective study

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Author(s)
Sung Eun KimNayoung KimJu Yup LeeKyung Sik ParkJeong Eun ShinKwangwoo NamHyeon Ju KimHyun Joo SongYoung-Eun JooDae-Seong MyungJi-Hyun SeoHyun Jin JoSeon Mie KimSeon Hee LimHyun Jin KimGwang Ho BaikSang Hyeon ChoiSuck Chei Choi
Keimyung Author(s)
Lee, Ju YupPark, Kyung Sik
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of neurogastroenterology and motility
Issued Date
2018
Volume
24
Issue
4
Keyword
Dyspepsia, Female, Gastrointestinal disorders, Risk factors
Abstract
Background/Aims: Functional dyspepsia (FD) is one of the most common gastrointestinal disorders, and FD imposes social and economic burden
worldwide. The aim of this study is to identify the prevalence and risk factors of FD in health check-up population in tertiary centers in
Korea.
Methods : A nationwide multicenter prospective study was performed at 9 tertiary healthcare centers in Korea between September 2016 and
June 2017. A total of 2525 subjects were investigated based on endoscopic findings and questionnaires with the Rome III criteria, and
Helicobacter pylori serology (IgG).
Results : A total of 1714 subjects without organic disease were enrolled. The mean (± SD) age was 51.5 (± 12.7) years, and 917 patients
(53.5%) were female. The proportion of H. pylori seropositivity was 51.0% (874/1714). The prevalence of FD was 10.3% (176/1714),
and the subtypes of postprandial distress syndrome alone, epigastric pain syndrome alone, and postprandial distress syndromeepigastric
pain syndrome overlap were 4.8%, 3.0%, and 2.5%, respectively. Multivariate analysis showed that female gender (OR,
1.58; 95% CI, 1.14-2.21) and education below college level (OR, 1.45; 95% CI, 1.01-2.07) were related to FD. Multivariate analysis
based on age 60 showed female gender as a significant (OR, 2.90; 95% CI, 1.06-7.94) factor in the group ≥ 60 years.
Conclusions : The prevalence of FD was 10.3% in the health check-up population in Korea. Female sex and education below college level were risk
factors for FD. Female sex is a risk factor for FD in old age, underscoring the need for close attention in this age group.
Keimyung Author(s)(Kor)
이주엽
박경식
Publisher
School of Medicine (의과대학)
Citation
Sung Eun Kim et al. (2018). The prevalence and risk factors of functional dyspepsia in health check-up participants: A nationwide multicenter prospective study. Journal of neurogastroenterology and motility, 24(4), 603–613. doi: 10.5056/jnm18068
Type
Article
ISSN
2093-0879
DOI
10.5056/jnm18068
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41536
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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