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Periodic Limb Movements During Sleep Are Not Associated With Hypertension in a Clinical Cohort of Korean Adults

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Author(s)
Dae-Seop ShinKwang Ik YangDoh-Eui KimYoung HwangboBrian B. KooYong Won Cho
Keimyung Author(s)
Cho, Yong Won
Department
Dept. of Neurology (신경과학)
Journal Title
American Journal of Hypertension
Issued Date
2018
Volume
31
Issue
11
Keyword
ethnicityhypertensionKoreanperiodic limb movementblood pressure
Abstract
BACKGROUND
There is growing evidence of increased cardiovascular risk including hypertension in patients with periodic limb movements during sleep (PLMS). In a multiethnic cohort study, the association between prevalent hypertension and PLMS varied according to ethnicity. We evaluated whether PLMS are associated with hypertension in Koreans.

METHODS
We enrolled 1,163 subjects who had polysomnography (PSG) from 2 tertiary hospitals. All subjects completed a sleep questionnaire before the PSG study. Coincidental hypertension was recorded according to past medical history. We analyzed the association between periodic limb movement index (PLMI), periodic limb movement associated with arousal index (PLMAI), and coincidental hypertension. Covariates were age, sex, body mass index (BMI), restless legs syndrome, apnea−hypopnea index (AHI), arousal index, and average oxygen saturation.

RESULTS
A total of 304 subjects (26.1%) had hypertension. The proportion of subjects with hypertension in the PLMI ≥ 15 category was higher than that in the PLMI< 15 category (32.4% vs. 25.0%; P = 0.04). The proportion of subjects with hypertension in the PLMAI ≥ 1 category was 32.6%, which was higher than that in the PLMAI < 1 category (24.6%; P = 0.02). In a multivariate regression model, neither PLMI (odds ratio [OR], 1.12; 95% confidence interval [CI] 0.75–1.68) nor PLMAI (OR, 1.21; 95% CI 0.83–1.76) were associated with hypertension. Statistical significance was found between coincidental hypertension and the following variables: age, smoking history, BMI, and AHI.

CONCLUSIONS
In a retrospective hospital-based study, there was no association between coincidental hypertension and PLMI/PLMAI in Koreans
Keimyung Author(s)(Kor)
조용원
Publisher
School of Medicine (의과대학)
Citation
Dae-Seop Shin et al. (2018). Periodic Limb Movements During Sleep Are Not Associated With Hypertension in a Clinical Cohort of Korean Adults. American Journal of Hypertension, 31(11), 1228–1233. doi: 10.1093/ajh/hpy114
Type
Article
ISSN
1941-7225
Source
https://academic.oup.com/ajh/article/31/11/1228/5056109
DOI
10.1093/ajh/hpy114
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41738
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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