계명대학교 의학도서관 Repository

Dose comparison between prescription methods according to anatomical variations in intracavitary brachytherapy for cervical cancer

Metadata Downloads
Affiliated Author(s)
최은철김옥배변상준김진희오영기
Alternative Author(s)
Choi, Eun CheolKim, Ok BaeByun, Sang JunKim, Jin HeeOh, Young Kee
Journal Title
Radiation Oncology Journal
ISSN
2234-3164
Issued Date
2018
Keyword
BrachytherapyAnatomyRadiation dosageUterine cervical neoplasmsVariation
Abstract
Purpose:
We compared how doses delivered via two-dimensional (2D) intracavitary brachytherapy (ICBT) and three dimensional (3D) ICBT varied anatomically.

Materials and Methods:
A total of 50 patients who received 30 Gy of 3D ICBT after external radiotherapy (RT) were enrolled. We compared the doses of the actual 3D and 2D ICBT plans among patients grouped according to six anatomical variations: differences in a small-bowel V2Gy, small bowel circumference, the direction of bladder distension, bladder volume, sigmoid V3.5Gy, and sigmoid circumference. Seven dose parameters were measured in line with the EMBRACE recommendations.

Results:
In terms of bladder volume, the bladder and small-bowel D2cc values were lower in the 150–250 mL bladder volume subgroup; and the rectum, sigmoid, and bladder D2mL values were all lower in the >250 mL subgroup, for 3D vs. 2D ICBT. In the sigmoid V3.5Gy >2 mL subgroup, the sigmoid and bladder D2mL values were significantly lower for 3D than 2D ICBT. The bladder D2mL value was also significantly lower for 3D ICBT, as reflected by the sigmoid circumference. In patients with a small bowel V2.0Gy >10 mL or small bowel circumference >15%, most dose parameters were significantly lower for 3D than 2D ICBT. The bladder distension direction did not significantly affect the doses.

Conclusion:
Compared to 2D ICBT, a greater bladder volume can reduce the internal 3D ICBT organ dose without affecting the target dose.
Department
Dept. of Radiation Oncology (방사선종양학)
Publisher
School of Medicine (의과대학)
Citation
Euncheol Choi et al. (2018). Dose comparison between prescription methods according to anatomical variations in intracavitary brachytherapy for cervical cancer. Radiation Oncology Journal, 36(3), 227–234. doi: 10.3857/roj.2018.00353
Type
Article
ISSN
2234-3164
DOI
10.3857/roj.2018.00353
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41800
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학)
Authorize & License
  • Authorize공개
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.