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Long-Term Outcomes of Antiviral Therapy in Patients With Advanced Chronic HBV Infection

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Author(s)
Hye Won LeeJun Yong ParkSang Gyune KimWon Young TakHyung Joon YimByoung Kuk JangMoon Young KimByung Ik KimJin-Woo LeeKi Tae YoonJae Youn CheongSo Young KwonTae Yeob KimSi Hyun BaeYeon Seok SeoJung Hyun KwonDong Joon KimJa-Kyung KimSoung Won JeongSungmin MyoungSang Hoon AhnKwang-Hyub Han
Keimyung Author(s)
Jang, Byoung Kuk
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical Gastroenterology and Hepatology
Issued Date
2019
Abstract
Hepatitis B virus (HBV) suppression with nucleot(s)ide analogue therapy reduces the risk of hepatic decompensation and hepatocellular carcinoma (HCC) in patients with advanced liver disease.1 In the present era of potent antiviral therapies, the prognostic significance of the serum HBV DNA level as a biological gradient has substantially diminished; the majority of treated patients achieve virologic suppression.2,3 After control of viremia, a higher baseline fibrosis level is a useful predictor for disease progression.4 Few “prospective” studies on the effects of antiviral agents, especially in chronic hepatitis B (CHB) patients with advanced liver disease, have been reported. Here, we investigated the long-term outcomes of antiviral treatment in patients with advanced liver disease.
Keimyung Author(s)(Kor)
장병국
Publisher
School of Medicine (의과대학)
Citation
Hye Won Lee et al. (2019). Long-Term Outcomes of Antiviral Therapy in Patients With Advanced Chronic HBV Infection. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2019.01.044
Type
Article
ISSN
1542-7714
Source
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1542356519300916
DOI
10.1016/j.cgh.2019.01.044
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41925
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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