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Comparison of Tc-99m DMSA Renal Planar Scan and SPECT for Detection of Cortical Defects in Infants with Suspected Acute Pyelonephritis

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Author(s)
Ga Eun KimJae Hyun ParkJoon Sik KimKyoung Sook WonHae Won Kim
Keimyung Author(s)
Kim, Ga EunPark, Jae HyunKim, Joon SikWon, Kyoung SookKim, Hae Won
Department
Dept. of Nursing (간호학)
Dept. of Pediatrics (소아청소년학)
Dept. of Nuclear Medicine (핵의학)
Journal Title
Indian Journal of Pediatrics
Issued Date
2019
Volume
86
Issue
9
Keyword
SPECTPyelonephritisInfantsTc-99m DMSA
Abstract
Objective
To compare the detection rate of Tc-99m dimercaptosuccinic acid (DMSA) renal single photon emission computerized tomography (SPECT) with that of planar scan for renal cortical defects in infants under one year of age with suspected acute pyelonephritis.

Methods
Sixty infants under one year of age who exhibited fever and pyuria were prospectively included in this study. All infants underwent concurrent Tc-99m DMSA renal planar scan and SPECT. Detection rates for cortical defects and the numbers of cortical defects in both kidneys were compared between Tc-99m DMSA planar scan and SPECT. The cortical defects were classified as large and small; the rate of discordant results was compared between subgroups.

Results
Negative findings by planar scan in 11 infants (11.3%) were modified to positive findings by SPECT. The detection rate of SPECT was significantly higher than that of planar scan (53.3% vs. 35.0%, p < 0.001). The numbers of cortical defects on SPECTwere significantly higher than those on planar scan (0.85 ± 0.97 vs. 0.53 ± 0.83, p < 0.001). A significantly higher rate of discordant results between the planar scan and SPECT was observed for the small cortical defects compared to the large cortical defects (48.6% vs. 14.3%, p = 0.029).

Conclusions
Tc-99mDMSA renal SPECTshowed a higher detection rate, compared with planar scan, for renal cortical defects in infants with suspected acute pyelonephritis. The study results suggest that, compared with planar scan, Tc-99m DMSA SPECT can detect small cortical defects with greater sensitivity
Keimyung Author(s)(Kor)
김가은
박재현
김준식
원경숙
김해원
Publisher
School of Medicine (의과대학)
College of Nursing (간호대학)
Citation
Ga Eun Kim et al. (2019). Comparison of Tc-99m DMSA Renal Planar Scan and SPECT for Detection of Cortical Defects in Infants with Suspected Acute Pyelonephritis. Indian Journal of Pediatrics, 86(9), 797–802. doi: 10.1007/s12098-019-02969-6
Type
Article
ISSN
0973-7693
Source
https://link.springer.com/article/10.1007%2Fs12098-019-02969-6
DOI
10.1007/s12098-019-02969-6
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42010
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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