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Clinical Characteristics and E cacy of Iron Treatment for Restless Legs Syndrome Patients with Very Low Ferritin Levels

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Author(s)
Tae-Joon KimJin-Sun JunKeun Tae KimTae-Won YangByeong-Su ParkJung-Ah LimJung-Ick ByunJun-Sang SunwooJung-Won ShinKi-Young Jung
Keimyung Author(s)
Kim, Keun Tae
Department
Dept. of Neurology (신경과학)
Journal Title
sleep medicine research
Issued Date
2018
Volume
9
Issue
2
Keyword
Restless legs syndromeFerritinIron
Abstract
Restless legs syndrome (RLS) is associated with dopaminergic dysfunction, and iron deficiency, manifesting as low ferritin. However, ferritin levels do not correlate well with demographic data. Based on the hypothesis that very low ferritin can accurately reflect clinical information, we herein described characteristics and treatment efficacy of RLS patients with ferritin levels under 15 ng/mL. We retrospectively reviewed 196 patients and collected clinical data. Twenty-one patients had ferritin levels under 15 ng/mL and were compared with those having ferritin levels over 15 ng/mL. The patients with very low ferritin levels were predominantly female, had earlier onset of symptoms, and showed a superior response to iron therapy. In conclusion, RLS patients with ferritin levels under 15 ng/mL showed distinct demographic features and treatment efficacy. Further studies on more patients with long-term follow-up are warranted to support this observation.
Keimyung Author(s)(Kor)
김근태
Publisher
School of Medicine (의과대학)
Citation
Tae-Joon Kim et al. (2018). Clinical Characteristics and E cacy of Iron Treatment for Restless Legs Syndrome Patients with Very Low Ferritin Levels. sleep medicine research, 9(2), 118–123. doi: 10.17241/smr.2018.00171
Type
Article
ISSN
2233-8853
Source
https://www.sleepmedres.org/journal/view.php?number=124
DOI
10.17241/smr.2018.00171
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42262
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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