계명대학교 의학도서관 Repository

Brachial-ankle Pulse Wave Velocity for Predicting Functional Outcomes in Patients With Cryptogenic Stroke

Metadata Downloads
Author(s)
Minho HanYoung Dae KimHyung Jong ParkIn Gun HwangJunghye ChoiJimin HaJi Hoe HeoHyo Suk Nam
Keimyung Author(s)
Park, Hyung Jong
Department
Dept. of Neurology (신경과학)
Journal Title
Journal of clinical neuroscience
Issued Date
2019
Volume
69
Keyword
Brachial-ankle pulse wave velocityCryptogenic strokePrognosisStroke
Abstract
Even after extensive standard evaluation, the probable cause of stroke in some patients remains unclear; this condition is defined as cryptogenic stroke (CS). The prognosis of patients with CS is largely undetermined. We investigated whether higher brachial-ankle pulse wave velocities (baPWVs) can predict poor functional outcomes at 3 months after stroke onset in these patients. We investigated patients with CS with first-ever acute cerebral infarction who underwent baPWV measurements. The stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale scores of >2 at 3 months after stroke onset. In total, 595 patients with CS were included; among them, 360 were men (60.5%). Their mean age was 65.0 ± 12.4 years. One-hundred-eleven patients (18.7%) had poor functional outcomes. In the multivariable logistic regression analysis, the cutoff baPWV value based on the receiver-operating characteristic curve was >1968 cm/s, which was determined as a strong independent predictor (OR 3.159, 95% CI 1.487–6.715, p = 0.003). The OR of the cutoff value was higher in the patients with CS with initial National Institutes of Health Stroke Scale (NIHSS) scores of ≥5 (OR 4.252, 95% CI 1.596–11.324, p = 0.004); that in the patients with initial NIHSS scores of <5 was not significant (OR 1.671, 95% CI 0.620–4.505, p = 0.310). baPWV measurement during the acute stroke phase might be useful in identifying patients with CS at high risks of having a poor neurological prognosis.
Keimyung Author(s)(Kor)
박형종
Publisher
School of Medicine (의과대학)
Citation
Minho Han et al. (2019). Brachial-ankle Pulse Wave Velocity for Predicting Functional Outcomes in Patients With Cryptogenic Stroke. Journal of clinical neuroscience, 69, 214–219. doi: 10.1016/j.jocn.2019.07.050
Type
Article
ISSN
1532-2653
Source
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0967586819308859
DOI
10.1016/j.jocn.2019.07.050
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42362
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.