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Clinical Significance of Early-Diastolic Tissue Velocity Imaging of Lateral Mitral Annulus for Prognosis of Nonischemic Left Ventricular Dysfunction

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Author(s)
Hyungseop KimIn-Cheol KimSang-Woong ChoiJin-Wook ChungJin Young Kim
Keimyung Author(s)
Kim, Hyung SeopKim, In CheolChung, Jin-WookKim, Jin Young
Department
Dept. of Internal Medicine (내과학)
Dept. of Radiology (영상의학)
Journal Title
Journal of clinical ultrasound
Issued Date
2019
Keyword
echocardiographyleft ventricular dysfunctiontissue velocity imaging
Abstract
Purpose:
We explored the potential of tissue velocity imaging (TVI) for prognosis of nonischemic left ventricular (LV) dysfunction (LVD).

Methods:
We reviewed 138 nonischemic LVD patients (58 ± 14 years) who underwent both cardiac magnetic resonance (CMR) and echocardiography. Septal and lateral mitral annular TVI data were compared with late gadolinium enhancement (LGE) on CMR. During a mean follow‐up of 24 months, recovery (>15%) of LV ejection fraction and clinical outcomes (cardiovascular death and heart failure hospitalization) were assessed.

Results:
LGE was commonly observed in the basal anteroseptal, inferoseptal, and inferior segments, but infrequently observed in the anterolateral segment. LGE was associated with lower early diastolic, septal (Sep‐e′ = 5.2 ± 2.0 vs 6.9 ± 2.0 cm/s, P = .031) and lateral (Lat‐e′ = 7.3 ± 3.0 vs 9.5 ± 2.0 cm/s, P < .001) TVI. The relationship between Lat‐e′ and anterolateral LGE (area under the curve, AUC 0.834) was much better than that between Sep‐e′ and inferoseptal LGE (AUC 0.699). The 60 patients with LVD reversibility revealed higher Lat‐e′ (9.8 ± 2.0 vs 6.7 ± 2.2 cm/s, P < .001) and lower LGE burden (7.3 ± 9.0 vs 22 ± 10%, P < .001), while Lat‐e′ ≤ 7.8 cm/s appeared unfavorable for 31 events patients. On multivariate analyses, Lat‐e′ (HR 0.79, 95% CI 0.63‐0.99, P = .044) and LVD reversibility (HR 0.53, 95% CI 0.16‐0.90, P = .018) were still meaningful together with LGE segments and burden.

Conclusion:
Lat‐e′ was related with LVD reversibility and a significant predictor of clinical outcomes.
Keimyung Author(s)(Kor)
김형섭
김인철
최상웅
정진욱
김진영
Publisher
School of Medicine (의과대학)
Citation
Hyungseop Kim et al. (2019). Clinical Significance of Early-Diastolic Tissue Velocity Imaging of Lateral Mitral Annulus for Prognosis of Nonischemic Left Ventricular Dysfunction. Journal of clinical ultrasound. doi: 10.1002/jcu.22787
Type
Article
ISSN
1097-0096
Source
https://onlinelibrary.wiley.com/doi/full/10.1002/jcu.22787
DOI
10.1002/jcu.22787
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42365
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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