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The impact of catheter ablation of atrial fibrillation on the left atrial volume and function: study using three-dimensional echocardiography

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Author(s)
Jongmin HwangHyoung-Seob ParkSeongwook HanSeung-Woon JunNa-Young KangJin-Hwa JeonSang-Woong ChoiCheol Hyun LeeIn-Cheol KimYun-Kyeong ChoHyuck-Jun YoonHyungseop KimChang-Wook NamSeung-Ho Hur
Keimyung Author(s)
Hwang, Jong MinPark, Hyoung SeobHan, Seong WookLee, Cheol HyunKim, In CheolCho, Yun KyeongYoon, Hyuck JunKim, Hyung SeopNam, Chang WookHur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing.
Issued Date
2020
Volume
57
Keyword
Atrial fibrillationAtrial remodelingCatheter ablationLeft atriumThree-dimensional echocardiography
Abstract
Purpose:
The exact correlation between the baseline left atrial (LA) volume (LAV) and atrial fibrillation (AF) radiofrequency catheter ablation (RFCA) outcomes and changes to the LA after AF RFCA has not yet been fully understood. We sought to evaluate the serial changes in the LAV and LA function after RFCA using 3D echocardiography.

Methods:
Consecutive patients who received RFCA of paroxysmal (PAF) or persistent AF (PeAF) at our center between January 2013 and March 2016 were included. Real-time 3D apical full-volume images were acquired, and a 3D volumetric assessment was performed using an automated three-beat averaging method. The LAV index (LAVI) was calculated and the LA ejection fraction (LAEF) was calculated as [LAVmax - LAVmin]/LAVmax.

Results:
Ninety-nine total patients were enrolled, and the mean age was 58.0 ± 8.2 years and 75 (74.7%) were male. There were 59 (59.6%) PAF patients and the remaining 40 (40.4%) had PeAF. AF recurred in 5 of 59 (8.5%) PAF and in 10 of 40 (25%) PeAF patients. The LAVImax increased on 1 day, decreased at 3 months, and then increased again at 1 year but was lower than that at baseline. The LAEF changes were similar to the volume changes but were more prominent in PeAF than PAF patients. The baseline 3D LAVImax was an independent predictor of AF recurrence after RFCA and the cut-off value was 44.13 ml/m2.

Conclusion:
In our study, even after 3 months of scar formation due to ablation, structural remodeling of the LA continued. The changes were more prominent in the non-recurrent, PeAF patients.
Keimyung Author(s)(Kor)
황종민
박형섭
한성욱
이철현
김인철
조윤경
윤혁준
김형섭
남창욱
허승호
Publisher
School of Medicine (의과대학)
Citation
Jongmin Hwang et al. (2020). The impact of catheter ablation of atrial fibrillation on the left atrial volume and function: study using three-dimensional echocardiography. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing., 57, 87–95. doi: 10.1007/s10840-019-00696-8
Type
Article
ISSN
1572-8595
Source
https://link.springer.com/article/10.1007%2Fs10840-019-00696-8
DOI
10.1007/s10840-019-00696-8
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42640
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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