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보존제가 없는 분말 형태의 트리암시놀론 아세토나이드를 이용한 내경계막의 시각화

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Author(s)
Kyung Tae KangUn Chul ParkHyeong Gon Yu
Keimyung Author(s)
Kang, Kyung Tae
Department
Dept. of Ophthalmology (안과학)
Journal Title
대한안과학회지
Issued Date
2020
Volume
61
Issue
5
Keyword
Internal limiting membraneMaculaPars plana vitrectomyTriamcinolone
Abstract
Purpose:
To evaluate and compare the degree of visualization of the vitreous and internal limiting membrane (ILM) during pars plana vitrectomy (PPV) using preservative-free triamcinolone acetonide (PF-TA) or triamcinolone acetonide suspension (TAS).

Methods:
We retrospectively analyzed the medical records of 61 eyes of 61 patients who underwent 25-gauge PPV and ILM peeling for various macular diseases. We assigned the patients to PF-TA and TAS groups, i.e., according to the type of triamcinolone acetonide used. The degree of visualization of the vitreous and ILM was classified into four different categories. The number of dye injections during PPV, need for indocyanine green (ICG), time elapsed before ILM peeling, and intraocular pressure (IOP) before surgery, 1 day and 1 month after surgery were determined.

Results:
The degree of visualization of the vitreous and ILM was significantly better in the PF-TA group compared with the TAS group. Although the number of dye injections during PPV was not different between the PF-TA and TAS groups (2.56 ± 0.07 and 2.37 ± 1.08, respectively, p = 0.06), the need for ICG was significantly different (6 and 22 eyes, respectively, p < 0.01). The time elapsed before ILM peeling was 185.68 ± 130.02 s in the PF-TA group and 411.15 ± 267.38 s in the TAS group (p < 0.01). The IOP was not different before or 1 day after surgery between the PF-TA and TAS groups, but was significantly different 1 month after surgery (12.88 ± 3.10 and 14.41 ± 2.91 mmHg, respectively, p = 0.03).

Conclusions:
Visualization of the vitreous and ILM was better when using PF-TA compared to TAS. PF-TA-assisted PPV could reduce the usage of ICG and was associated with a reduced latency to ILM peeling. Because this was in turn associated with a lower IOP at postoperative 1 month, PF-TA was safer and more effective than TAS.
Alternative Title
Preservative-free Triamcinolone Acetonide-assisted Visualization of the Internal Limiting Membrane
Keimyung Author(s)(Kor)
강경태
Publisher
School of Medicine (의과대학)
Citation
Kyung Tae Kang et al. (2020). 보존제가 없는 분말 형태의 트리암시놀론 아세토나이드를 이용한 내경계막의 시각화. 대한안과학회지, 61(5), 506–513. doi: 10.3341/jkos.2020.61.5.506
Type
Article
ISSN
2092-9374
Source
http://www.jkos.org/journal/view.html?uid=11486&page=&sort=&scale=10&all_k=&s_t=%EB%B3%B4%EC%A1%B4%EC%A0%9C%EA%B0%80+%EC%97%86%EB%8A%94+%EB%B6%84%EB%A7%90+%ED%98%95%ED%83%9C%EC%9D%98+%ED%8A%B8%EB%A6%AC%EC%95%94%EC%8B%9C%EB%86%80%EB%A1%A0+%EC%95%84%EC%84%B8%ED%86%A0%EB%82%98%EC%9D%B4%EB%93%9C%EB%A5%BC+%EC%9D%B4%EC%9A%A9%ED%95%9C+%EB%82%B4%EA%B2%BD%EA%B3%84%EB%A7%89%EC%9D%98+%EC%8B%9C%EA%B0%81%ED%99%94&s_a=&s_k=&s_v=&s_n=&spage=&pn=search&year=&vmd=Full
DOI
10.3341/jkos.2020.61.5.506
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42781
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
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